Endogenous Growth Factors and Nutrients in the Healing Wound

  • Wes J. Arlein
  • Michael D. Caldwell
Part of the Serono Symposia USA Norwell, Massachusetts book series (SERONOSYMP)


This chapter focuses on the temporal sequence of endogenous growth factors and nutrients in the healing wound. We propose that the function and proliferation of wound cells are dependent on the concentration of substrates, hormones, growth factors, cytokines, matrix, etc. in the local wound environment and less dependent on serum factors. The consistent proliferative effect of early wound fluid and inhibitory effect of late wound fluid is supportive of this hypothesis (1).


Keratinocyte Growth Factor Wound Fluid Peptide Growth Factor Epidermal Growth Factor Family Endogenous Growth Factor 
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© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Wes J. Arlein
  • Michael D. Caldwell

There are no affiliations available

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