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Pharmacological Treatment of Painful Diabetic Neuropathy

  • Chapter
Clinical Management of Diabetic Neuropathy

Part of the book series: Contemporary Endocrinology ((COE,volume 7))

Abstract

Pain is a subjective symptom of major clinical importance as it is often this complaint that motivates patients to seek healthcare. Pain is often associated with disability and is suggested as an important factor in affecting quality of life (1). About 11% of the adult population has persistent pain and additional 5% experience temporary pain (1). Neurogenic pain is defined as pain caused by dysfunction of the peripheral or central nervous system, in the absence of nociceptor (nerve terminal) stimulation by trauma or disease. Other terms used to describe some forms of neurogenic pain include neuropathic pain and deafferentation pain, and central pain. Neurogenic pain is common, accounting for at least 25% of the patients attending most pain clinics. When all categories of neurogenic pain syndromes are taken into account, there are probably >550,000 cases in the UK population at any one time, giving a prevalence of approx 1%. The incidence of neurogenic pain increases with age, accounting for one third of all pain-clinic patients aged >65 and one half of those aged >70 (2).

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Authors
  1. Dan Ziegler MD
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  1. Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Aristidis Veves MD

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Ziegler, D. (1998). Pharmacological Treatment of Painful Diabetic Neuropathy. In: Veves, A. (eds) Clinical Management of Diabetic Neuropathy. Contemporary Endocrinology, vol 7. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-1816-6_10

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  • DOI: https://doi.org/10.1007/978-1-4612-1816-6_10

  • Publisher Name: Humana Press, Totowa, NJ

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