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Improvement of Lactic Cell Production

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Biotechnology for Fuels and Chemicals

Part of the book series: Applied Biochemistry and Biotechnology ((ABAB))

Abstract

The production of Lactobacillus brevis has been improved by changing the medium composition and the physiological conditions. The cellular concentration reaches 8.2 × 1010 cells/mL in 21 h with a fed-batch technique in MRS medium. Freeze-drying has been used as technology for drying the cells and survival rates have been improved with different additives such as glycerol, CaCO3, and skimmed-milk powder up to 70%. A model has been developed to predict the stability of freeze-dried cultures during long-term conservation. This model, based on Arrhenius equation, has been confirmed by experimental data.

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© 1998 Springer Science+Business Media New York

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Desmons, S., Krhouz, H., Evrard, P., Thonart, P. (1998). Improvement of Lactic Cell Production. In: Finkelstein, M., Davison, B.H. (eds) Biotechnology for Fuels and Chemicals. Applied Biochemistry and Biotechnology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-1814-2_47

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  • DOI: https://doi.org/10.1007/978-1-4612-1814-2_47

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-7295-3

  • Online ISBN: 978-1-4612-1814-2

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