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Portal Hypertension/GI Bleeding

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Diseases of the Liver and Bile Ducts

Part of the book series: Current Clinical Practice ((CCP))

Abstract

In portal hypertension, the increase of portal pressure is due to both an increase in vascular resistance and splanchnic blood flow (1–3). Prehepatic, intrahepatic, and posthepatic sites of increased resistance to portal venous blood flow may result in portal hypertension (1). Prehepatic and posthepatic portal hypertension are caused by obstruction of the portal and hepatic veins, respectively. Intrahepatic portal hypertension may be the result of anatomic alterations of the hepatic lobule with secondary compression of portal venules, sinusoids, and hepatic venules, and functional derangement of the intrahepatic microcirculation.

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Authors
  1. Maram Zakko
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  2. Roberto Groszmann
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Editors and Affiliations

  1. University of Connecticut School of Medicine, Farmington, CT, USA

    George Y. Wu MD, PhD

  2. Hartford Hospital, Hartford, CT, USA

    Jonathan Israel MD

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Zakko, M., Groszmann, R. (1998). Portal Hypertension/GI Bleeding. In: Wu, G.Y., Israel, J. (eds) Diseases of the Liver and Bile Ducts. Current Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-1808-1_29

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  • DOI: https://doi.org/10.1007/978-1-4612-1808-1_29

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-7293-9

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