Abstract
Imagine a 20-year-old college student diagnosed with Hodgkin’s’ disease, facing chemotherapy that will be likely to cause ovarian failure and render her sterile. Imagine too a 35-year-old woman, unmarried and rising rapidly in the ranks of a major corporation. She is aware that her biological clock is ticking, but also that taking time off work at this time to have children may impede her career progress and perhaps make her forfeit her dream of becoming a CEO. Will there be a time when women can cryopreserve their oocytes for future use? If the oocytes are never used, can they be placed in a bank for use by unrelated women? Imagine a couple that has undergone IVF, and after two cycles have three healthy children, but have embryos cryopreserved that they never want to use, but wish to donate to other infertile couples. What of “ orphaned” embryos, no longer wanted by the couples who produced them. Will there ever be a time when these excess embryos can be banked, for use by women or couples who cannot conceive on their own, or who have genetic conditions that make them unwilling to pass on their DNA? The era of oocyte and embryo banking is rapidly approaching. The ART literature is beginning to expand to include ideas about oocyte and embryo cryopreservation and banking.1 This chapter outlines the state of the art in oocyte and embryo cryopreservation and speculates about how oocyte and embryo banking may be organized in the future.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Carroll J. Development of oocyte banks and systems for the in-vitro development of oocytes: future directions for the treatment of infertility. Hum Reprod. 1996; 11: 159–168.
Semprini AE, Levi-Setti P, Bozzo M, Ravizza M, Taglioretti A, Sulpizio P, Albani E, Oneta M, Pardi G. Insemination of HIV-negative women with processed semen of HIV-positive partners. Lancet. 1992; 340: 1317–1319.
Semprini AE, Levi-Setti PE, Bozzo M, et al. Reproductive counseling and assistance to HIV-discordant couples. Int Conf AIDS. 1993 June 6–11; 9: 75. Abstract WS-B32-2.
Rayos AA, Takahashi Y, Hishinuma M, Kanagawa H. Quick freezing of unfertilized mouse oocytes using ethylene glycol with sucrose or trehalose. J Reprod Fertil. 1994; 100: 123–129.
Van der Elst J, Nerinckx S, Van Steirteghem AC. Association of ultrarapid freezing of mouse oocytes with increased polyploidy at the pronucleate stage, reduced cell numbers in blastocysts and impaired fetal development. J Reprod Fertil. 1993; 99: 25–32.
Vincent C, Gamier V, Heyman Y, Renard JP. Solvent effects on cytoskeletal organization and in-vitro survival after freezing of rabbit oocytes. J Reprod Fertil. 1989; 87: 809–820.
Baka SG, Toth TL, Veeck LL, Jones HW Jr, Muasher SJ, Lanzendorf SE. Evaluation of the spindle apparatus of in-vitro matured human oocytes following cryopreservation. Hum Reprod. 1995; 10: 1817–1820.
Carroll J, Warnes GM, Matthews CD. Increase in digyny explains polyploidy after in vitro fertilization of frozen-thawed mouse oocytes. J Reprod Fertil. 1989; 85: 489–494.
Gook DA, Osborn SM, Bourne H, Johnston WIH. Fertilization of human oocytes following cryopreservation; normal karyotypes and absence of stray chromosomes. Hum Reprod. 1994; 9: 684–691.
Toth TL, Baka SG, Veeck LL, Jones HW Jr, Muasher S, Lanzendorf SE. Fertilization and in-vitro development of cryopreserved human prophase I oocytes. Fertil Steril. 1994; 62: 891–894.
Gook DA, Schiewe MC, Osborn SM, Asch RH, Jansen RPS, Johnston WIH. Intracytoplasmic sperm injection and embryo development of human oocytes cryopreserved using 1, 2-propanediol. Hum Reprod. 1995; 10: 2367–2641.
van Uem JF, Siebzehnrubl ER, Schuh B, Koch R, Trotnow S, Lang N. Birth after cryopreservation of unfertilized oocytes [letter]. Lancet. 1987; 1: 752–753.
Chen C. Pregnancy after human oocyte cryopreservation. Lancet 1986; 1: 884–886.
Roussi M, Royere M, Guillonueau M, Lansac J, Muh JP. Human antral fluid IGF-1 and oocyte maturity: effect of stimulation therapy. Acta Endocrinol. 1989; 121: 90–94.
Pieters MH, Dumoulin JC, Engelhart CM, Bras M, Evers JL, Geraedts JP. Immaturity and aneuploidy in human oocytes after different stimulation protocols. Fertil Steril. 1991; 56: 306–310.
Gomez E, Tarin JJ, Pellicer A. Oocyte maturation in humans: the role of gonadotropins and growth factors. Fertil Steril. 1993; 60: 40–46.
Lorenzo PL, Illera MJ, Illera JC, Illera M. Enhancement of cumulus expansion and nuclear maturation during bovine oocyte maturation in vitro by the addition of epidermal growth factor and insulin-like growth factor I. J Reprod Fertil. 1994; 101: 696–701.
Alak BM, Smith GD, Woodruff TK, Stouffer RL, Wolf DP. Enhancement of primate oocyte maturation and fertilization in vitro by inhibin A and activin A. Fertil Steril. 1996; 66: 646–653.
Totey SM, Singh G, Taneja M, Pawshe CH, Talwar GP. In vitro maturation, fertilization and development of follicular oocytes from buffalo. J Reprod Fertil. 1992; 95: 597–607.
Prins GS, Wagner C, Weidel L, Gianfortoni J, Marut EL, Scommegna A. Gonadotropins augment maturation and fertilization of human immature oocytes cultured in vitro. Fertil Steril. 1987; 47: 1035–1037.
Flood JT, Chillik CF, van Uem JF, Iritani A, Hodgen GD. Ooplasmic transfusion: prophase germinal vescicle oocytes made developmentally competent by microinjection of metaphase II egg cytoplasm. Fertil Steril. 1990; 53: 1049–1054.
Racowsky C, Kaufman ML. Nuclear degeneration and meiotic aberrations observed in human oocytes matured in vitro: analysis by light microscopy. Fertil Steril. 1992; 58: 750–755.
Cha KY, Koo JJ, Ko JJ, Choi DH, Han SY, Yoon TK. Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program. Fertil Steril. 1991; 55: 109–113.
Nagy ZP, Cecile J, Liu J, Loccufier A, Devroey P, Van Steirteghem A. Pregnancy and birth after intracytoplasmic sperm injection of in vitro matured germinal-vescicle stage oocytes: case report. Fertil Steril. 1996; 65: 1047–1050.
Trounson A, Wood C, Kausche A. In vitro maturation and the fertilization and developmental competence of oocytes recovered from untreated polycystic ovarian patients. Fertil Steril. 1994; 62: 353–362.
Barnes FL, Crombie A, Gardner DK, et al. Blastocyst development and birth after in-vitro maturation of human primary oocytes, intracytoplasmic sperm injection and assisted hatching. Hum Reprod. 1995; 10: 3243–3247.
Saunders DM, Porter RN, Persson JW, Ryan J. Should we consider freezing oocytes as part of surgical management in young single women? Aust NZ J Surg. 1996; 66: 64.
Frydman R, Rainhorn JD, Forman R, et al. Programmed oocyte retrieval during routine laparoscopy and embryo cryopreservation for later transfer. Am J Obstet Gynecol. 1986; 155: 112–117.
Gosden RG, Oktay K, Rutherford AJ, Radford JA. Ovarian tissue banking. 52nd Annual American Society of Reproductive Medicine Meeting, John B Hynes Convention Center, Boston, MA, Nov. 2–6, 1996, Video Presentation-05, p 82.
Revel F, Mermillod P, Peynot N, Renard JP, Heyman Y. Low developmental capacity of in vitro matured and fertilized oocytes from calves compared with that of cows. J Reprod Fertil. 1995; 103: 115–120.
Check JH, Askari HA, Fisher C, Vanaman L. The use of a shared donor oocyte program to evaluate the effect of uterine senescence. Fertil Steril. 1994; 61: 252–256.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Ginsburg, E.S. (1998). Developments in Embryo and Oocyte Banking. In: Sauer, M.V. (eds) Principles of Oocyte and Embryo Donation. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1640-7_19
Download citation
DOI: https://doi.org/10.1007/978-1-4612-1640-7_19
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-7226-7
Online ISBN: 978-1-4612-1640-7
eBook Packages: Springer Book Archive