Abstract
A basic feature of programmed cell death/apoptosis in vivo is that cells within a population die at very different times even following an apparently identical signal to die. Nowhere is this more obvious than in the developing nervous system where neurons in the same population often die over several days. In fact, “naturally occurring” cell death in the developing nervous system was overlooked for a long time because of its sporadic asynchronous nature and the relatively short period of time cells show morphological signs of death.
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Pittman, R.N., Messam, C.A., Mills, J.C. (1999). Asynchronous Death as a Characteristic Feature of Apoptosis. In: Koliatsos, V.E., Ratan, R.R. (eds) Cell Death and Diseases of the Nervous System. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-1602-5_2
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DOI: https://doi.org/10.1007/978-1-4612-1602-5_2
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