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Dysplasia and Cancer

  • Chapter
Operative Strategies in Inflammatory Bowel Disease

Abstract

The risk of cancer in ulcerative colitis (UC) is well known and this topic has been thoroughly discussed in Chapter 4 (Riddell). In the past this risk was considered to increase exponentially with the duration of disease. In fact, it was considered to be 25% at 20 years and 34% to 43% over 25 years (1,2). These data were gathered from patients admitted to referral centers. Further prospective studies on patient populations in circumscribed areas have led to a lower figure (3–6). Moreover, the routine use of endoscopy and the widespread knowledge of histopathological premalignant patterns such as dysplasia (7,8) have deeply modified the attitude of physicians. In fact, many centers are carrying out programs of endoscopic and histologic surveillance in long-standing colitis attempting to better detect malignant modifications in their early stages. The dicussion has arisen in the past and still continues today about the usefulness of such programs and their cost-effectiveness (9–12).

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Authors
  1. Gilberto Poggioli
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  2. Luca Stocchi
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  3. Antonino Cavallari
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Editor information

Editors and Affiliations

  1. Section of General Surgery, University of Chicago, Chicago, IL, 60637, USA

    Fabrizio Michelassi MD (Professor and Chief) (Professor and Chief)

  2. Division of Colon and Rectal Surgery, Mount Sinai Medical Center, New York, NY, 10029, USA

    Jeffrey W. Milsom MD (Professor and Chief) (Professor and Chief)

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© 1999 Springer Science+Business Media New York

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Poggioli, G., Stocchi, L., Cavallari, A. (1999). Dysplasia and Cancer. In: Michelassi, F., Milsom, J.W. (eds) Operative Strategies in Inflammatory Bowel Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1396-3_15

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  • DOI: https://doi.org/10.1007/978-1-4612-1396-3_15

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7130-7

  • Online ISBN: 978-1-4612-1396-3

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