Abstract
The L isomer of DABA, 2,4-diaminobutyric acid, is a major component of the polymixin group of antibiotics and a component of bacterial cell walls and of certain Lathyrus and related seeds (1–2). It was found to be neurotoxic in rats and mice (3), though it may not be neurotoxic in humans. L-DABA is widely distributed in nature (4).
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References
Ressler, C., Restone, P.A., and Ehrenberg, R.H. Science 134, 188, 1961.
Bell, E.A., and Tirimana, A.S.L. Biochem. J. 97, 104, 1965.
Kessel, D. Fed. Proc. Fed. Amer. Chem. Soc. Exp. Biol. 18, 258, 1959.
Chen, C.H., Flory, W., and Koeppe, R.E. Tox. and Appl. Pharmacology23, 334, 1972.
Erecinska, M., Troeger, M.B., and Alston, T.A. J. Neurochem. 46, 1452, 1986.
Iversen, L.L., and Johnston, G.A.R. J. Neurochem. 18, 1939, 1971.
Roskoski, R. J. Neurochem. 36, 1236, 1981.
Simon, J.R., Martin, D.L., and Kroll, M. J. Neurochem. 23, 981, 1974.
Radian, R., and Kanner, B.I. Biochemistry. 26, 1236, 1983.
O’Neal, R.M., Chen, C.H., Reynolds, C.S., Meghal, S.K., and Koeppe, R.E. Biochem. J. 106, 699, 1968.
Horton, R.W., Collins, J.F., Anlezark, G.M., and Meldrum, B.S. Eur. J. Pharmacol. 59, 75, 1979.
Bichard, A.R., and Little, H.J. Br. J. Pharmacol. 76, 447, 1982.
Rostain, J.C., Wardley-Smith, B., Forni, C., and Halsey, M.J. Neuropharmacol. 25, 5, 545, 1986.
Meldrum, B.S., Croucher, M.J., and Krogsgaard-Larsen, R. Excerpta Medica, 182, 1982.
Hinazumi, H., and Mitsui, T. Acta Cryst. B27, 2152, 1971.
Fugler-Domenico, L., Russell, C.S., and Sapse, A.M. Struct. Chem. 1, 379, 1990.
Schlegel, H.B. J. Comp. Chem.3, 214, 1982.
Iverson, L.L., and Kelly, J.S. Biochem. Pharmacol. 24, 933, 1975.
Krogsgaard-Larsen, R.J. Med. Chem. 24, 1377, 1981.
Debler, E.A., and Lajtha, A. J. Neurochem. 48, 1851, 1987.
Ramek, M. Int. J. Quantum Chem. Quantum Biol. Symp. 17, 45, 1990.
Ramek, M. Structural Chem. 6, 1, 15, 1995.
Ramek, M. Int. J. Quantum Chem. Quantum Biol. Symp. 21, 79, 1994.
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Sapse, AM. (2000). The Diaminobutyric (DABA), Delta Aminopentanoic, and Epsilon Aminohexanoic Acids. In: Molecular Orbital Calculations for Amino Acids and Peptides. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4612-1354-3_4
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DOI: https://doi.org/10.1007/978-1-4612-1354-3_4
Publisher Name: Birkhäuser, Boston, MA
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