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Nonparametric locally efficient estimation of the Treatment Specific Survival distribution with right Censored Data and Covariates in Observational Studies

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Part of the book series: The IMA Volumes in Mathematics and its Applications ((IMA,volume 116))

Abstract

In many observational studies one is concerned with comparing treatment specific survival distributions in the presence of confounding factors and censoring. In this paper we develop locally efficient point and interval estimators of these survival distributions which adjust for confounding by using an estimate of the propensity score and concurrently allow for dependent censoring. The proposed methodology is an application of a general methodology for construction of locally efficient estimators as presented in Robins (1993) and Robins and Rotnitzky (1992). The practical performance of the methods are tested with a simulation study.

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© 2000 Springer Science+Business Media New York

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Hubbard, A.E., van der Laan, M.J., Robins, J.M. (2000). Nonparametric locally efficient estimation of the Treatment Specific Survival distribution with right Censored Data and Covariates in Observational Studies. In: Halloran, M.E., Berry, D. (eds) Statistical Models in Epidemiology, the Environment, and Clinical Trials. The IMA Volumes in Mathematics and its Applications, vol 116. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1284-3_3

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  • DOI: https://doi.org/10.1007/978-1-4612-1284-3_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7078-2

  • Online ISBN: 978-1-4612-1284-3

  • eBook Packages: Springer Book Archive

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