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Peritonitis: Management of the Patient with SIRS and MODS

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Multiple Organ Failure

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Abstract

Peritonitis continues to be a complex illness that requires the coordinated efforts of timely surgical intervention, systemic antibiotic therapy, and supportive critical care management. Peritonitis and its accompanying sequela of intraabdominal abscess are frequently associated with activation of the systemic inflammatory response syndrome (SIRS) and is commonly associated with the development of the multiple organ dysfunction syndrome (MODS). Many authors consider peritonitis to be the prototypical infection associated with MODS, although there is general consensus at the present time that any infectious source could potentially activate SIRS and lead to MODS.1 The general perception is that effective intervention in the initial management of patients with peritonitis can avoid subsequent evolution of the multiple organ failure cascade. Some have reported reversal of organ failure with surgical intervention in intraabdominal infection.2–4 This chapter summarizes the significant aspects of the treatment of the complex constellation of diseases called peritonitis.

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Authors
  1. Donald E. Fry
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Editors and Affiliations

  1. Department of Surgery, St. Louis University Hospital, St. Louis, Missouri, 63110, USA

    Arthur E. Baue MD (Professor Emeritus) (Professor Emeritus)

  2. Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, D-81377, Germany

    Eugen Faist MD (Professor) (Professor)

  3. Department of Surgery, School of Medicine, University of New Mexico, Albuquerque, New Mexico, 87131, USA

    Donald E. Fry MD (Professor and Chairman) (Professor and Chairman)

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© 2000 Springer Science+Business Media New York

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Fry, D.E. (2000). Peritonitis: Management of the Patient with SIRS and MODS. In: Baue, A.E., Faist, E., Fry, D.E. (eds) Multiple Organ Failure. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1222-5_27

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  • DOI: https://doi.org/10.1007/978-1-4612-1222-5_27

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7049-2

  • Online ISBN: 978-1-4612-1222-5

  • eBook Packages: Springer Book Archive

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