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Leukocyte—Endothelial Cell Interactions: Review of Adhesion Molecules and Their Role in Organ Injury

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Book cover Multiple Organ Failure

Abstract

The causes of multiple organ injury, which are likely multifactorial, include microcirculatory vasoconstriction, local organ inflammatory mediator production, endothelial activation, and inappropriate polymorphonuclear neutrophil (PMN) sequestration and activation. This review focuses on leukocyteendothelial interactions involving neutrophils and leading to tissue injury.

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Authors
  1. Milind S. Shrotri
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  2. James C. Peyton
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  3. William G. Cheadle
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Editor information

Editors and Affiliations

  1. Department of Surgery, St. Louis University Hospital, St. Louis, Missouri, 63110, USA

    Arthur E. Baue MD (Professor Emeritus) (Professor Emeritus)

  2. Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, D-81377, Germany

    Eugen Faist MD (Professor) (Professor)

  3. Department of Surgery, School of Medicine, University of New Mexico, Albuquerque, New Mexico, 87131, USA

    Donald E. Fry MD (Professor and Chairman) (Professor and Chairman)

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© 2000 Springer Science+Business Media New York

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Shrotri, M.S., Peyton, J.C., Cheadle, W.G. (2000). Leukocyte—Endothelial Cell Interactions: Review of Adhesion Molecules and Their Role in Organ Injury. In: Baue, A.E., Faist, E., Fry, D.E. (eds) Multiple Organ Failure. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1222-5_24

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  • DOI: https://doi.org/10.1007/978-1-4612-1222-5_24

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7049-2

  • Online ISBN: 978-1-4612-1222-5

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