Intraabdominal fibrous adhesions are a major cause of intestinal obstruction.1 By far the most common cause of intraabdominal adhesions is previous surgical intervention. Most surgeons regard intraabdominal adhesions as a problem, because reoperation on the abdomen is made difficult by prolonged dissection of fibrous adhesions with the risk of visceral damage. Because adhesions may have such serious consequences, it is not surprising that a very large number of techniques have been devised with the aim of preventing their development. Many of these however have been shown to be unreliable. 1,2 Many of the techniques used have been of an empirical nature, and little improvement can be expected unless the underlying pathogenesis is understood because a clear understanding of pathogenesis is a prerequisite to rational prophylaxis and therapy.
KeywordsPermeability Starch Ischemia Adenosine Histamine
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- 2.Connolly JE, Smith JW. The prevention and treatment of intestinal adhesions. Surg Gynecol Obstet 1960; 110:417–431.Google Scholar
- 3.Hertzler AE. The Peritoneum, Vol. 1. St. Louis: Mosby, 1919.Google Scholar
- 6.Eskeland G. Regeneration of parietal peritoneum. 1. A light microscopical study. Acta Pathol Microbiol Scand 1966; 68:355–378.Google Scholar
- 13.Eskeland G. Growth of autologous peritoneal fluid cells in intraperitoneal diffusion chambers in rats. A light microscopical study. Acta Pathol Microbiol Scand 1966; 68:481–500.Google Scholar
- 14.Eskeland G, Kjaerheim A. Regeneration of parietal peritoneum in rats. 2. An electron microscopical study. Acta Pathol Microbiol Scand 1966; 68:379–395.Google Scholar
- 15.Eskeland G, Kjaerheim A. Growth of autologous peritoneal fluid cells in intraperitoneal diffusion chambers in rats. 2. An electron microscopical study. Acta Pathol Microbiol Scand 1966; 68:501–516.Google Scholar
- 19.Watters WB, Buck RC. Mitotic activity of peritoneum in contact with a regenerating area of peritoneum. Virchows Arch Abt B Zellpathol 1973; 13:48–54.Google Scholar
- 34.Raftery AT. The effect of urine and bile in the peritoneal cavity: a histological and f ibrinolytic study in the rat. Ann R Coll Surg Engl 1980; 62:380.Google Scholar
- 38.Hartwell SW. The Mechanics of Healing in Human Wounds. Springfield: Thomas, 1955:109.Google Scholar