The Biology of Peritoneal Tissue Repair

  • Andrew T. Raftery


Intraabdominal fibrous adhesions are a major cause of intestinal obstruction.1 By far the most common cause of intraabdominal adhesions is previous surgical intervention. Most surgeons regard intraabdominal adhesions as a problem, because reoperation on the abdomen is made difficult by prolonged dissection of fibrous adhesions with the risk of visceral damage. Because adhesions may have such serious consequences, it is not surprising that a very large number of techniques have been devised with the aim of preventing their development. Many of these however have been shown to be unreliable. 1,2 Many of the techniques used have been of an empirical nature, and little improvement can be expected unless the underlying pathogenesis is understood because a clear understanding of pathogenesis is a prerequisite to rational prophylaxis and therapy.


Mesothelial Cell Adhesion Formation Fibrinolytic Activity Wound Surface Parietal Peritoneum 
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© Springer Science+Business Media New York 2000

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  • Andrew T. Raftery

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