Abstract
Pelvic inflammatory disease (PID) is the most common major complication of sexually transmitted pathogens among young women and is associated with significant medical and economic consequences.1 An estimated 1 million women are treated annually for PID in the United States2, 3; in 1990 there were approximately 200,000 hospitalized cases of PID.4 Washington and Katz5 estimated that for 1990 annual costs associated with PID were $4.2 billion and projected that these costs would rise to approach $10 billion by the year 2000. Of increasing concern has been the recognition that significant adverse reproductive sequelae are associated with PID. One-fourth of women who experience an episode of acute PID subsequently develop one or more such long-term sequelae. The most common and most important of these is involuntary tubal factor infertility, which occurs in approximately 20%.6, 7 Ectopic pregnancies occur at a six- to tenfold increased rate following acute PID.6 In addition, other important sequelae such as chronic pelvic pain, dyspareunia, pelvic adhesions, and inflammatory residua occur in 15% to 20% of cases. Such complications often lead to major surgical intervention, including total abdominal hysterectomy and bilateral salpingo-oophorectomy.
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Sweet, R.L. (1997). Microbial Etiology of Pelvic Inflammatory Disease. In: Landers, D.V., Sweet, R.L. (eds) Pelvic Inflammatory Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-0671-2_3
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