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Microbial Etiology of Pelvic Inflammatory Disease

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Pelvic Inflammatory Disease

Abstract

Pelvic inflammatory disease (PID) is the most common major complication of sexually transmitted pathogens among young women and is associated with significant medical and economic consequences.1 An estimated 1 million women are treated annually for PID in the United States2, 3; in 1990 there were approximately 200,000 hospitalized cases of PID.4 Washington and Katz5 estimated that for 1990 annual costs associated with PID were $4.2 billion and projected that these costs would rise to approach $10 billion by the year 2000. Of increasing concern has been the recognition that significant adverse reproductive sequelae are associated with PID. One-fourth of women who experience an episode of acute PID subsequently develop one or more such long-term sequelae. The most common and most important of these is involuntary tubal factor infertility, which occurs in approximately 20%.6, 7 Ectopic pregnancies occur at a six- to tenfold increased rate following acute PID.6 In addition, other important sequelae such as chronic pelvic pain, dyspareunia, pelvic adhesions, and inflammatory residua occur in 15% to 20% of cases. Such complications often lead to major surgical intervention, including total abdominal hysterectomy and bilateral salpingo-oophorectomy.

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Sweet, R.L. (1997). Microbial Etiology of Pelvic Inflammatory Disease. In: Landers, D.V., Sweet, R.L. (eds) Pelvic Inflammatory Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-0671-2_3

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