Abstract
The ability of humans to maintain their normal physiological functions involves many complex interwoven biological pathways. Part of this homeostasis involves normal turnover of tissues found throughout the body. In addition, it involves the ability of mammalian tissues to repair themselves after injury. Without the ability of tissues to repair themselves, we would be unable to withstand the trauma of daily life or the invasion of bacteria, fungi, and viruses. In addition, the ability to heal after chemical, mechanical, electrical, and biological trauma makes life as we know it possible. In this chapter, we will discuss how healing occurs and what processes are involved. As we discuss below, healing is a multistep process that involves biological components found in blood and elements that make up extracellular matrix. These elements are components of systems that prevent excessive bleeding, remove exogenous debris, promote new tissue deposition, and allow resumption of normal physiological processes. The scope of this chapter is to discuss the relationship between these components and systems that promote homeostasis.
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Silver, F.H., Christiansen, D.L. (1999). Wound Healing. In: Biomaterials Science and Biocompatibility. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-0557-9_9
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DOI: https://doi.org/10.1007/978-1-4612-0557-9_9
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