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Nuclear Analytical Methods in the Life Sciences pp 177–187Cite as

Trace Elemental Content of Biological Materials

A Comparison of NAA and ICP-MS Analysis

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Abstract

The advantages and disadvantages of neutron activation analysis (NAA) and inductively coupled plasma-source mass spectrometry (ICP-MS) for the analysis of biological materials is reviewed.

Comparison is made between NAA (instrumental) and ICP-MS (conventional pneumatic solution nebulization and laser ablation) analysis of the biological reference material National Bureau of Standards (NBS) SRM 1577 Bovine Liver. Relatively good agreement is achieved between the results for the 18 elements analyzed by both techniques and those either certified or reported in the literature. Elemental concentrations for Li, Mg, AI, Ca, Cr, Mn, Fe, Cu, Zn, Br, Rb, and Cs are also reported for IAEA Mixed Human Diet (H9), NBS SRM 909 Human Serum, and NBS SRM 1577a Bovine Liver, analyzed by solution nebulization ICP-MS.

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Author information

Authors and Affiliations

  1. Department of Chemistry, University of Surrey Guildford, Surrey, GU2 5XH, UK

    Neil I. Ward, Fadi R. Abou-Shakra & Steven F. Durrant

Authors
  1. Neil I. Ward
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  2. Fadi R. Abou-Shakra
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  3. Steven F. Durrant
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Editor information

Editors and Affiliations

  1. National Institute of Standards and Technology, Gaithersburg, MD, USA

    Rolf Zeisler

  2. University of California, Irvine, CA, USA

    Vincent P. Guinn

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Ward, N.I., Abou-Shakra, F.R., Durrant, S.F. (1990). Trace Elemental Content of Biological Materials. In: Zeisler, R., Guinn, V.P. (eds) Nuclear Analytical Methods in the Life Sciences. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0473-2_20

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  • DOI: https://doi.org/10.1007/978-1-4612-0473-2_20

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6777-5

  • Online ISBN: 978-1-4612-0473-2

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