Drug Discovery pp 377-388 | Cite as

Chenodeoxycholic Acid and Ursodeoxycholic Acid

  • Robert A. Maxwell
  • Shohreh B. Eckhardt


Cholelithiasis (gallstones) is a major medical and economic problem in the USA (Schoenfield, 1977; Schoenfield et al., 1981). It has been estimated to have a prevalence of 15 million women and five million men, and almost one million new cases are discovered each year (Ingelfinger, 1968; Friedman et al., 1966). Gallstones account for 5000–8000 deaths and a toll of $1 billion annually (Schoenfield et al, 1981).


Bile Acid Bile Salt Cholic Acid Ursodeoxycholic Acid Chenodeoxycholic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Robert A. Maxwell
    • 1
  • Shohreh B. Eckhardt
    • 2
  1. 1.The Wellcome Research Laboratories ResearchTriangle ParkUSA
  2. 2.University of Vermont College of MedicineBurlingtonUSA

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