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Drug Discovery pp 377–388Cite as

Chenodeoxycholic Acid and Ursodeoxycholic Acid

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Abstract

Cholelithiasis (gallstones) is a major medical and economic problem in the USA (Schoenfield, 1977; Schoenfield et al., 1981). It has been estimated to have a prevalence of 15 million women and five million men, and almost one million new cases are discovered each year (Ingelfinger, 1968; Friedman et al., 1966). Gallstones account for 5000–8000 deaths and a toll of $1 billion annually (Schoenfield et al, 1981).

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Authors and Affiliations

  1. The Wellcome Research Laboratories Research, Triangle Park, North Carolina, USA

    Robert A. Maxwell

  2. University of Vermont College of Medicine, Burlington, Vermont, USA

    Shohreh B. Eckhardt

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  1. Robert A. Maxwell
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© 1990 Springer Science+Business Media New York

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Maxwell, R.A., Eckhardt, S.B. (1990). Chenodeoxycholic Acid and Ursodeoxycholic Acid. In: Drug Discovery. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0469-5_28

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  • DOI: https://doi.org/10.1007/978-1-4612-0469-5_28

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6775-1

  • Online ISBN: 978-1-4612-0469-5

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