Drug Discovery pp 377-388 | Cite as

Chenodeoxycholic Acid and Ursodeoxycholic Acid

  • Robert A. Maxwell
  • Shohreh B. Eckhardt


Cholelithiasis (gallstones) is a major medical and economic problem in the USA (Schoenfield, 1977; Schoenfield et al., 1981). It has been estimated to have a prevalence of 15 million women and five million men, and almost one million new cases are discovered each year (Ingelfinger, 1968; Friedman et al., 1966). Gallstones account for 5000–8000 deaths and a toll of $1 billion annually (Schoenfield et al, 1981).


Cholesterol Diarrhea Gall Lactose Constipation 


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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Robert A. Maxwell
    • 1
  • Shohreh B. Eckhardt
    • 2
  1. 1.The Wellcome Research Laboratories ResearchTriangle ParkUSA
  2. 2.University of Vermont College of MedicineBurlingtonUSA

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