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Trace Elements, Micronutrients, and Free Radicals pp 77–105Cite as

Dietary Prooxidants

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Part of the book series: Contemporary Issues in Biomedicine, Ethics, and Society ((CIBES))

Abstract

The oxidative breakdown of membrane lipids is considered a possible mechanism of irreversible injury of the cell. The present review analyzes the actual knowledge so far achieved on different dietary forms of cell damage, giving special emphasis to the proofs in favor of the pathogenetic involvement of lipid peroxidation. The alimentary conditions characterized by increased lipid peroxidation levels are the supplementation with polyunsaturated fatty acids, the ethanol intoxication, the iron overload, and the feeding rich in orotic acid. Whereas a conclusive relationship between lipid peroxidation and cell damage has not yet been obtained in these experimental conditions, an increasing bulk of data strongly support such a correlation.

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    Ivor E. Dreosti

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Dianzani, M.U. (1991). Dietary Prooxidants. In: Dreosti, I.E. (eds) Trace Elements, Micronutrients, and Free Radicals. Contemporary Issues in Biomedicine, Ethics, and Society. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0419-0_4

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