Preliminary Results of HLA Class I and Class II Antigens in Chinese with Nasopharyngeal Carcinoma ◊
Simons et al. (1) were the first to report an association between nasopharyngeal carcinoma (NPC) and HLA antigens in Chinese patients. Expanded studies on 153 patients by Simons et al. (2) showed a borderline increase in HA A2 and Bw46. Simons et al..(3)reviewed the data collected during the Second Asia-Oceania Histocompatibility Workshop with respect to NPC in Chinese. The close linkage disequilibrium between Bw46 and DRw9 in controls was not seen in NPC patients but there was a high frequency of blanks. The HLA profile showed differences between newly diagnosed patients and long-term survivors.
Unable to display preview. Download preview PDF.
- 1.M.J. Simons, G.B. Wee et al., Lancet I: 142–143 (1975). 2. MJ Simons, GB Wee et al., Natl Cancer Inst Monogr 47:147–151 (1977).Google Scholar
- 3.M.J. Simons, S.H. Chan et al., Proceedings of the Second Asia and Oceania Histocompatibility Workshop Conference. Immunopublishing, Toorak, Australia p369 (1981).Google Scholar
- 4.S.H.Chan,C.T.Chew et al., Aizawa M(ed). HLA in Asia-Oceania. Hokkaido, University Press, Hokkaido Japan p396 (1986).Google Scholar
- 5.M.J. Simons. Hawkins BR (eds.) Human leucocyte antigens in Chinese. Hong Kong University Press, Hong Kong (1987).Google Scholar
- 6.J.A. Danilov, G. Ayoub et al, Terasaki,T.(ed) Histocompatibility Testing 1980. Los Angeles, UCLA Tissue Typing Laboratory, p287 (1980)Google Scholar
- 9.B. Dupont (ed) Immunobiology of HLA, vol 1, Histocompatibility Testing 1987. Springer-Verlag, New York (1989).Google Scholar