Preliminary Results of HLA Class I and Class II Antigens in Chinese with Nasopharyngeal Carcinoma ◊
Simons et al. (1) were the first to report an association between nasopharyngeal carcinoma (NPC) and HLA antigens in Chinese patients. Expanded studies on 153 patients by Simons et al. (2) showed a borderline increase in HA A2 and Bw46. Simons et al..(3)reviewed the data collected during the Second Asia-Oceania Histocompatibility Workshop with respect to NPC in Chinese. The close linkage disequilibrium between Bw46 and DRw9 in controls was not seen in NPC patients but there was a high frequency of blanks. The HLA profile showed differences between newly diagnosed patients and long-term survivors.
KeywordsNasopharyngeal Carcinoma Human Leucocyte Antigen Central Province Viral Capsid Antigen Joint Occurrence
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