Preliminary Results of HLA Class I and Class II Antigens in Chinese with Nasopharyngeal Carcinoma

  • M. G. Hammon
  • M. M. Hsu
  • J. Y. Ko
  • R. P. Hsieh
  • C. S. Yang
Part of the Experimental Biology and Medicine book series (EBAM, volume 24)


Simons et al. (1) were the first to report an association between nasopharyngeal carcinoma (NPC) and HLA antigens in Chinese patients. Expanded studies on 153 patients by Simons et al. (2) showed a borderline increase in HA A2 and Bw46. Simons et al..(3)reviewed the data collected during the Second Asia-Oceania Histocompatibility Workshop with respect to NPC in Chinese. The close linkage disequilibrium between Bw46 and DRw9 in controls was not seen in NPC patients but there was a high frequency of blanks. The HLA profile showed differences between newly diagnosed patients and long-term survivors.


Nasopharyngeal Carcinoma Human Leucocyte Antigen Central Province Viral Capsid Antigen Joint Occurrence 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • M. G. Hammon
    • 1
    • 4
  • M. M. Hsu
    • 2
  • J. Y. Ko
    • 2
  • R. P. Hsieh
    • 3
  • C. S. Yang
    • 1
  1. 1.Graduate Institute of MicrobiologyCollege of Medicine,National Taiwan UniversityTaiwan, ROC
  2. 2.Departments of OtolaryngologyCollege of Medicine,National Taiwan UniversityTaiwan, ROC
  3. 3.Clinical Pathology College of MedicineCollege of Medicine,National Taiwan UniversityTaiwan, ROC
  4. 4.Transplantation UnitThe Natal Institute of ImmunologyDurbanUSA

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