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Epstein-Barr Virus and Human Disease · 1990 pp 201–206Cite as

Role of the Epstein-Barr Virus (EBV) Glycoprotein GP350 as a Target Antigen for EBV-Specific Cellular Killing

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Part of the book series: Experimental Biology and Medicine ((EBAM,volume 24))

Abstract

By using a new model of human lymphoid cells with a strong and stable expression of the transfected Epstein-Barr virus glycoprotein 350 (gp350) gene, we illustrate here that the gp350 molecule serves as target for the EBV-specific antibody mediated cellular cytotoxicity. Interestingly, mouse monoclonal antibodies to gp350 do not seem to be able to mediate such a cellular killing activity.

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References

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Author information

Authors and Affiliations

  1. Laboratory of Immunovirology, University of Montreal and St-Justine Hospital, Canada

    M. Khyatti & J. Menezes

  2. Immunology Research Center, Institut Armand-Frappier, Laval, Canada

    P. C. Patel

Authors
  1. M. Khyatti
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  2. P. C. Patel
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  3. J. Menezes
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Editor information

D. V. Ablashi A. T. Huang J. S. Pagano G. R. Pearson C. S. Yang Kristinë L. Ablashi

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© 1991 Springer Science+Business Media New York

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Khyatti, M., Patel, P.C., Menezes, J. (1991). Role of the Epstein-Barr Virus (EBV) Glycoprotein GP350 as a Target Antigen for EBV-Specific Cellular Killing. In: Ablashi, D.V., Huang, A.T., Pagano, J.S., Pearson, G.R., Yang, C.S., Ablashi, K.L. (eds) Epstein-Barr Virus and Human Disease · 1990. Experimental Biology and Medicine, vol 24. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0405-3_31

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  • DOI: https://doi.org/10.1007/978-1-4612-0405-3_31

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6747-8

  • Online ISBN: 978-1-4612-0405-3

  • eBook Packages: Springer Book Archive

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