Abstract
Testing for specific anti-EBV antibodies is frequently used to obtain serological evidence for acute EBV infection. To date this is predominantly performed by indirect immunofluorescence staining of infected cells or by ELISAs based on the cell culture-derived antigen material. However, these assays are difficult to standardize and the variability of culture systems as well as the complexity of the phase-specific antigens do not support their use for large-scale production. The utilization of recombinant EBV antigens might overcome the aforementioned difficulties and improve the serodiagnosis of EBV infection.
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Hinderer, W. et al. (1991). Recombinant EBV Antigens and Their Diagnostic Value. In: Ablashi, D.V., Huang, A.T., Pagano, J.S., Pearson, G.R., Yang, C.S., Ablashi, K.L. (eds) Epstein-Barr Virus and Human Disease · 1990. Experimental Biology and Medicine, vol 24. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0405-3_19
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DOI: https://doi.org/10.1007/978-1-4612-0405-3_19
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-4612-6747-8
Online ISBN: 978-1-4612-0405-3
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