Abstract
Successful treatment of alcoholism is generally dependent on an early diagnosis. Consequently, there is a clinical need for objective and reliable markers of alcohol consumption, since valid information of alcohol intake cannot be obtained from subjects misusing alcohol. This chapter describes two new biochemical markers of alcohol consumption: carbohydrate-deficient transferrin (CDT) in serum and 5-hydroxytryptophol (5-HTOL) in urine. It gives information about biochemical background and clinical characteristics and describes recent method developments to enable their use in clinical routine work. Because they show different clinical profiles, how they can be used in combination in a clinical setting monitoring alcohol consumption is also illustrated.
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Borg, S., Beck, O., Helander, A., Voltaire, A., Stibler, H. (1992). Carbohydrate-Deficient Transferrin and 5-Hydroxytryptophol. In: Litten, R.Z., Allen, J.P. (eds) Measuring Alcohol Consumption. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0357-5_7
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DOI: https://doi.org/10.1007/978-1-4612-0357-5_7
Publisher Name: Humana Press, Totowa, NJ
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