Advertisement

Effects of Acute Hypertension on Pial Artery Tone

  • George Osol
Part of the Vascular Biomedicine book series (VB)

Abstract

The arteries that course along the surface of the brain normally operate in a state of partial, sustained constriction (tone) from which either dilation or constriction may occur, as required to maintain normal blood flow. Although its extent varies with arterial size and experimental conditions, basal tone appears to be a widespread vascular phenomenon that has been observed in cerebral arteries from a number of species, in vivo and in vitro (e.g., refs. 1-3). Some degree of arterial constriction is requisite for cerebral blood flow (CBF) autoregulation, which is principally effected by arterial dilation to decreases, and by constriction to increases in transmural pressure.

Keywords

Cerebral Blood Flow Transmural Pressure Basal Tone Hypertensive Encephalopathy Acute Hypertension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Busija, D. W., Heistad, D. D., and Marcus, M. L. (1981) Am. J. Physiol. 241 H228–H234.PubMedGoogle Scholar
  2. 2.
    Vinall, P. E. and Simeone, F. A. (1981) Stroke 12 640–642.PubMedCrossRefGoogle Scholar
  3. 3.
    Osol, G. and Halpern, W. (1985) Am. J. Physiol. 249, H914–H921.PubMedGoogle Scholar
  4. 4.
    Johnson, P. C. (1986) Circ. Res. 59 483–495.PubMedCrossRefGoogle Scholar
  5. 5.
    Mayrovitz, H. N. and Roy, J. (1983) Am. J. Physiol. 245, H1031–H1038.PubMedGoogle Scholar
  6. 6.
    Heistad, D. D. and Marcus, M. L. (1978) Circ. Res. 45,331–338.CrossRefGoogle Scholar
  7. 7.
    Tamaki, K. T., Sadoshima, S., Baumbach, G. L., Iadecola, C., Reis, D. J., and Heistad, D. D. (1984)Hypertension 6(Suppl. 1) I-75-I-81.CrossRefGoogle Scholar
  8. 8.
    Skinhoj, E. and Strandgaard, S. (1973) Lancet 1, 461–462.PubMedCrossRefGoogle Scholar
  9. 9.
    MacKenzie, E. T., Strandgaard, S., Graham, D. I., Jones, J. V., Harper, A. M., and Farrar, J. K. (1976) Circ. Res. 39 33–41.PubMedCrossRefGoogle Scholar
  10. 10.
    Strandgaard, S., MacKenzie, E. T., Sengupta, D., Rowan, J. P., Lassen, N. A., and Harper, A. M. (1974) Circ. Res. 34,435–440.PubMedCrossRefGoogle Scholar
  11. 11.
    Johansson, B., Strandgaard, S., and Lassen, N. A. (1974) Circ. Res. 34–35 I-167-I-174.Google Scholar
  12. 12.
    Johansson, B. B. (1978) Stroke 9 588–590.PubMedCrossRefGoogle Scholar
  13. 13.
    Mayhan, W. G. and Heistad, D. D. (1985) Am. J. Physiol. 248, H712–H718.PubMedGoogle Scholar
  14. 14.
    Nag, S., Robertson, D. M., and Dinsdale, H. B. (1977) Lab. Investig. 36, 150–161.PubMedGoogle Scholar
  15. 15.
    Werber, A. H. and Heistad, K. K. (1984) Circ. Res. 55,286–294.PubMedCrossRefGoogle Scholar
  16. 16.
    Byrom, F. B. (1954) Lancet 2,201–211.CrossRefGoogle Scholar
  17. 17.
    Auer, L. M. (1978) Acta. Neurochir. (Wein) 27(Suppl.), 1–11.Google Scholar
  18. 18.
    Kontos, H. A., Wei, E. P., Dietrich, W. E., Narari, R. M., Povlishock, J. T., Ghatak, N. R., Ellis, E. F., and Patterson, J. L., Jr. (1981) Am. J. Physiol. 240, H511–H527.PubMedGoogle Scholar
  19. 19.
    Baumbach, G. L. and Heistad, D. D. (1985) Am. J. Physiol. 249, H629–H637.PubMedGoogle Scholar
  20. 20.
    Fukasawa, H. (1969) Tohoku J. Exp. Med. 99,255–268.PubMedCrossRefGoogle Scholar
  21. 21.
    Kontos, H. A., Wei, E. P., Navari, R. M., Lavasseur, J. E., Rosenblum, W. I., Patterson, J. L., Jr. (1978) Am. J. Physiol. 234, H371–H383.PubMedGoogle Scholar
  22. 22.
    Kontos, H. A. (1985) Cir. Res. 57,508–516.CrossRefGoogle Scholar
  23. 23.
    Harder, D. R. (1987) Circ. Res. 60,102–107.PubMedCrossRefGoogle Scholar
  24. 24.
    Harder, D. R., Sanchez-Ferrer, C., Kauser, K., Stekiel, W. J., and Rubanyi, G. M. (1989) Circ. Res. 65,193–198.PubMedCrossRefGoogle Scholar
  25. 25.
    Kuo, L., Chilian, W. M., and Davis, M. J. (1990) Circ. Res. 66, 860–866.PubMedCrossRefGoogle Scholar
  26. 26.
    Falcone, J. C., Davis, M. J., and Meininger, G. A. (1991) Am. J. Physiol. 260, H130–H135.PubMedGoogle Scholar
  27. 27.
    McCarron, J., Osol, G., and Halpern, W. (1990) Blood Vessels 26,315–319.Google Scholar
  28. 28.
    Meininger, G. A. and Davis, M. J. (1992) Am. J. Physiol. 263, H647–H659.PubMedGoogle Scholar
  29. 29.
    Osol, G., Osol, R., and Halpem, W. (1988) Proceedings of the Second Symposium on Resistance Arteries, Perinatology, New York, pp. 162–169.Google Scholar
  30. 30.
    Halpem, W., Osol, G., and Coy, G. (1984) Ann. Biomed. Eng. 12,463–479.CrossRefGoogle Scholar
  31. 31.
    Osol, G. and Halpem, W. (1985) Am. J. Physiol. 249, H914–H921.PubMedGoogle Scholar
  32. 32.
    Mayhan, W. G., Faraci, F. M., and Heistad, D. D. (1987) Am. J. Physiol. 253, H1435–H1440.PubMedGoogle Scholar
  33. 33.
    Luscher, T. F., Raij, L., and Vanhoutte, P. M. (1987) Hypertension 9, 157–163.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • George Osol

There are no affiliations available

Personalised recommendations