Abstract
Although few physicians would debate the role of an immune pathogenesis for most patients with asthma, recent progress in the pharmacologic treatment of asthma has led some to believe that immunologie mechanisms are irrelevant if the patient’s disease can be controlled with appropriate drugs. Other physicians take a different view; they regard the identification of relevant sensitizing antigens as paramount to the patient’s appropriate treatment. The subset of extrinsic noninfectious asthma is believed to represent 30–50% of the total number of patients with reversible obstructive lung disease (1). Prevalence statistics tend to be misleading; sensitization, particularly to pollen, requires several seasons of exposure. Immunologie mechanisms are, therefore, infrequently detected in children under the age of 4 yr in whom infections seem to be the predominant triggering event. Between age 6 and 25 yr, a much larger percentage of patients will fall into the latter atopic class of extrinsic asthma; with increasing age, the number steeply diminishes.
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Nagy, S.M. (1994). Allergic Evaluations and Management Considerations of Patients with Asthma. In: Gershwin, M.E., Halpern, G.M. (eds) Bronchial Asthma. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0297-4_9
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DOI: https://doi.org/10.1007/978-1-4612-0297-4_9
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