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Ascorbic Acid and Gastrointestinal Cancer

  • Chapter
Nutrients in Cancer Prevention and Treatment

Part of the book series: Experimental Biology and Medicine ((EBAM,volume 27))

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Abstract

A literature review was made to critically evaluate the ability of ascorbic acid to modulate the incidence of gastrointestinal cancer. A comparison of preclinical, clinical, and epidemiological studies indicated that evidence for ascorbic acid as an inhibitor of carcinogenesís is stronger with regard to gastric cancer and weaker with regard to esophageal and colon/rectal cancer. Insufficient evidence currently exists regarding the oral cavity and the use of ascorbic acid in precancerous conditions such as polyposis.

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Authors and Affiliations

  1. Hoffmann-La Roche Inc., Nutley, NJ, 07110, USA

    Marvin Cohen & Hemmi N. Bhagavan

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  1. Marvin Cohen
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Editors and Affiliations

  1. University of Colorado Health Sciences Center, Denver, CO, USA

    Kedar N. Prasad PhD

  2. University of Pavia, Italy

    Leonida Santamaria MD

  3. Cancer Treatment Center of America, Des Moines, IA, USA

    R. Michael Williams MD, PhD

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Cohen, M., Bhagavan, H.N. (1995). Ascorbic Acid and Gastrointestinal Cancer. In: Prasad, K.N., Santamaria, L., Williams, R.M. (eds) Nutrients in Cancer Prevention and Treatment. Experimental Biology and Medicine, vol 27. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0237-0_7

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  • DOI: https://doi.org/10.1007/978-1-4612-0237-0_7

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6675-4

  • Online ISBN: 978-1-4612-0237-0

  • eBook Packages: Springer Book Archive

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