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Immunity, Infection, and Nasal Disease

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Book cover Diseases of the Sinuses

Abstract

Mucosal surfaces provide interfaces between the external and internal environments through which gases, nutrients, waste products, and other materials move. The properties of host mucosal surfaces that allow for these functions also provide ideal sites for the entry of microbial pathogens. Probably for this reason, the immune system developed defensive components with functions specialized for mucosal areas. These include mucus and its constituents, secretory immunoglobulins, and unique subsets of leukocytes that localize to or maturate in mucosal regions. They function to prevent attachment of microbes to host tissues and thereby prevent entry, and to signal and mobilize other immune components if entry has been achieved.

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Yoshida, S.H., Gershwin, M.E. (1996). Immunity, Infection, and Nasal Disease. In: Gershwin, M.E., Incaudo, G.A. (eds) Diseases of the Sinuses. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0225-7_19

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  • DOI: https://doi.org/10.1007/978-1-4612-0225-7_19

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6670-9

  • Online ISBN: 978-1-4612-0225-7

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