Effects of Pressure Pulsation on Oxygen Transfer Rate Measured by Sulfite Method

Part of the Applied Biochemistry and Biotechnology book series (ABAB)


Pressure pulsation (PP) was investigated for its effects on oxygen transfer rate (OTR) measured by sulfite oxidation. By manipulating airflow rate, 0.41–1.2 vvm, and a control valve in a 4-L bioreactor, the frequency of PP was varied at different gas pressures3–15 psig. A mathematical model of OTR was built and compared to experimental data. OTR was also examined at constant gas pressure, 4.5–15.0 psig. The results indicate a good agreement between measurement and model prediction. OTR above 9 psig during PP showed significant enhancement at 25°C. This proves that PP not only affects the elevation of DO level, but also increases the interfacial area and mass transfer coefficient.

Index Entries

Oxygen transfer pressure pulsation sulfite oxidation 


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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Wei-Cho Huang
    • 1
  • Cheng S. Gong
    • 1
  • George T. Tsao
    • 1
  1. 1.School of Chemical EngineeringPurdue UniversityWest LafayetteUSA

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