• Michael J. Klein


Osteomyelitis is the inflammation of bone and bone marrow, usually secondary to an infectious agent. It can be hematogenous or following a trauma. Children have a higher incidence of infection in the metaphysis of long bones and adults in axial skeletal. Staphylococcus aureus is the more frequent culprit. In intravenous drug users, Pseudomonas is common. Salmonella has a predilection for patients with sickle cell disease. Irregular areas of radiolucency are later associated with the formation of a sinus tract and osteosclerosis. Findings in a small biopsy will vary significantly with the area biopsied and disease time: acute inflammation, necrosis, or chronic active inflammation. Systemic antibiotic is the treatment of choice. For all cases, the cure rate is considered above 90 %.


Osteomyelitis Infection Bone Bacteriological culture 

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Copyright information

© Springer-Verlag London 2015

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory MedicineHospital for Special SurgeryNew YorkUSA

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