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Benign Notochordal Cell Tumor

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Tumors and Tumor-Like Lesions of Bone

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Abstract

Benign notochordal tumor is a benign indolent bone tumor probably derived from vestigial notochordal rests. As it is usually asymptomatic, its true incidence is unknown but has been found in 20 % of spines in an autopsy study. Radiographs, CT, or bone scan may appear normal. MRI shows altered signal intensity. Histologically, it appears as sheet-like proliferation of bland-looking cells with well-defined boundary, resembling fatty marrow at low magnification. Foci of chordoma may be found next to the lesion, suggesting histogenetic relationship. It is immunohistochemically positive for S100, epithelial markers, and brachyury. Surgery is only indicated in large lesions and for differential diagnosis.

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Authors and Affiliations

  1. Laboratory of Anatomic Pathology, Kyoto University Hospital, Kyoto, Japan

    Yasuaki Nakashima MD, PhD

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  1. Yasuaki Nakashima MD, PhD
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Correspondence to Yasuaki Nakashima MD, PhD .

Editor information

Editors and Affiliations

  1. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Eduardo Santini-Araujo

  2. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Ricardo K. Kalil

  3. Villa Erbosa Hospital, University of Bologna, Bologna, Italy

    Franco Bertoni

  4. Department of Pathology, Kyung Hee University Hospital, Seoul, Korea, Republic of (South Korea)

    Yong-Koo Park

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© 2015 Springer-Verlag London

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Nakashima, Y. (2015). Benign Notochordal Cell Tumor. In: Santini-Araujo, E., Kalil, R., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, London. https://doi.org/10.1007/978-1-4471-6578-1_38

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  • DOI: https://doi.org/10.1007/978-1-4471-6578-1_38

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-6577-4

  • Online ISBN: 978-1-4471-6578-1

  • eBook Packages: MedicineMedicine (R0)

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