Abstract
Fibrosarcoma of bone is a malignant spindle cell tumor characterized by a herringbone or fascicular disposition of atypical, monomorphic fibroblasts and is always negative for any specific marker, which makes this tumor a diagnosis of exclusion. It can be primary or, less frequently, secondary to radiation or other pathologic conditions. It represents from 2 % to 4 % of primary bone tumors and is reported to occur from the second to the seventh decades of life. Fibrosarcoma has a preference for the metaphyses of long bones, especially the distal femur. The more important prognostic feature is histological grade. Wide resection or amputation is the indicated treatment.
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Kalil, R.K. (2015). Fibrosarcoma of Bone. In: Santini-Araujo, E., Kalil, R., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, London. https://doi.org/10.1007/978-1-4471-6578-1_29
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DOI: https://doi.org/10.1007/978-1-4471-6578-1_29
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