Fibrosarcoma of Bone
Fibrosarcoma of bone is a malignant spindle cell tumor characterized by a herringbone or fascicular disposition of atypical, monomorphic fibroblasts and is always negative for any specific marker, which makes this tumor a diagnosis of exclusion. It can be primary or, less frequently, secondary to radiation or other pathologic conditions. It represents from 2 % to 4 % of primary bone tumors and is reported to occur from the second to the seventh decades of life. Fibrosarcoma has a preference for the metaphyses of long bones, especially the distal femur. The more important prognostic feature is histological grade. Wide resection or amputation is the indicated treatment.
KeywordsFibrosarcoma Bone Malignant Tumor Undifferentiated Sarcoma
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