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Chondromyxoid Fibroma

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Book cover Tumors and Tumor-Like Lesions of Bone

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Abstract

Chondromyxoid fibroma is a benign tumor composed of spindle or stellate cells forming lobules and with abundant myxoid and/or chondroid intercellular material. There is a male predominance. More than half of the cases develop in the second and third decades of life. Most cases of CMF occur in the metaphysis of tubular bones of the lower extremity. Approximately one-third of the cases are diagnosed around the knee joint, and the proximal tibial metaphysis is the most common site of involvement, followed by the distal femoral metaphysis. Rarely, there are reports of cases that involve flat bones. Radiologically, sharply circumscribed radiolucent lesion with an elongated shape is seen. Cortical expansion, exuberant endosteal sclerosis, and coarse trabeculation can be seen. The primary and preferable treatment of chondromyxoid fibroma should be en bloc resection.

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Authors and Affiliations

  1. Department of Pathology, Kyung Hee University School of Medicine, Seoul, South Korea

    Yong-Koo Park MD, PhD

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  1. Yong-Koo Park MD, PhD
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Correspondence to Yong-Koo Park MD, PhD .

Editor information

Editors and Affiliations

  1. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Eduardo Santini-Araujo

  2. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Ricardo K. Kalil

  3. Villa Erbosa Hospital, University of Bologna, Bologna, Italy

    Franco Bertoni

  4. Department of Pathology, Kyung Hee University Hospital, Seoul, Korea, Republic of (South Korea)

    Yong-Koo Park

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© 2015 Springer-Verlag London

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Park, YK. (2015). Chondromyxoid Fibroma. In: Santini-Araujo, E., Kalil, R., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, London. https://doi.org/10.1007/978-1-4471-6578-1_22

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  • DOI: https://doi.org/10.1007/978-1-4471-6578-1_22

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-6577-4

  • Online ISBN: 978-1-4471-6578-1

  • eBook Packages: MedicineMedicine (R0)

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