Abstract
Chondroblastoma is a benign cartilage-forming neoplasm occurring in the epiphyses of immature long bones. It is more common in male. The peak incidence is between 10 and 25 years of age. Typically, chondroblastoma occurs in the epiphyses of the long bones. More than 75 % of the cases develop at the epiphyseal and epimetaphyseal region of the distal and proximal femur, proximal tibia, and proximal humerus. Radiologically, chondroblastoma is usually located in the medullary portion and arises either at the epiphysis or apophysis of the long tubular bone. Extension to the metaphysis can be seen at times. The lesion consists in well-defined, geographic bone destruction with either a spherical or an oval shape. There are amorphous calcific foci within the lesion. Histologically, the basic cells are chondroblast. There are randomly distributed multinucleated giant cells. Immature chondroid matrix that appears as variably sized nodules composed of light-staining, amorphous, bluish to eosinophilic material surrounded by chondroblasts is typically present.
Most chondroblastomas are appropriately treated by curettage.
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Park, YK. (2015). Chondroblastoma. In: Santini-Araujo, E., Kalil, R., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, London. https://doi.org/10.1007/978-1-4471-6578-1_21
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