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Tumors and Tumor-Like Lesions of Bone pp 235–240Cite as

High-Grade Surface Osteosarcoma

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Abstract

High-grade surface osteosarcoma is a high-grade bone-forming neoplasm which arises on the surface of the bone. It has a male predominance. Peak incidence is in the second decade of life. A majority of patients are in the second and third decades of life. Radiologically, the lesion presents a large mass with a broad-based attachment to the underlying bone. There is a dense to moderate mineralization with a fluffy immature appearance. There is partial cortical destruction and periosteal new bone. Histologically, it is identical to conventional osteosarcoma (osteoblastic, chondroblastic, fibroblastic subtypes). All tumors are high grade. Treatment consists of neoadjuvant chemotherapy followed by surgical resection with a wide margin.

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Recommended Reading

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Author information

Authors and Affiliations

  1. Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA

    Carrie Y. Inwards MD

  2. College of Medicine, Mayo Clinic, Rochester, MN, USA

    Carrie Y. Inwards MD

  3. Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN, USA

    Doris Wenger MD

Authors
  1. Carrie Y. Inwards MD
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  2. Doris Wenger MD
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Corresponding author

Correspondence to Carrie Y. Inwards MD .

Editor information

Editors and Affiliations

  1. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Eduardo Santini-Araujo

  2. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Ricardo K. Kalil

  3. Villa Erbosa Hospital, University of Bologna, Bologna, Italy

    Franco Bertoni

  4. Department of Pathology, Kyung Hee University Hospital, Seoul, Korea, Republic of (South Korea)

    Yong-Koo Park

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© 2015 Springer-Verlag London

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Inwards, C.Y., Wenger, D. (2015). High-Grade Surface Osteosarcoma. In: Santini-Araujo, E., Kalil, R., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, London. https://doi.org/10.1007/978-1-4471-6578-1_15

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  • DOI: https://doi.org/10.1007/978-1-4471-6578-1_15

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-6577-4

  • Online ISBN: 978-1-4471-6578-1

  • eBook Packages: MedicineMedicine (R0)

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