Graft vs Host Disease and Skin Manifestations

  • Min Kin Derek Ho
  • Noah Scheinfeld


Graft-versus-host disease (GVHD) has a multitude of manifestations, but the most common organ involved is the skin. There are two main forms of the GVHD are acute GVHD and chronic GVHD: acute and chronic. We discuss the immunology of this fascinating syndrome seen in bone marrow transplant patients, and the skin disease that accompanies them.


Allogenic Lichen planus Wickham’s striae Scleroderma Extracorporeal photophoresis Sicca syndrome Poikiloderma 

Suggested Reading

  1. Filopovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. diagnosis and staging working group. Biol Blood Marrow Transplant. 2005;11(12):945–56.CrossRefGoogle Scholar
  2. Hymes SR, Turner ML, Champlin RE, Couriel DR. Cutaneous manifestations of chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2006;12(11):1101–13.PubMedCrossRefGoogle Scholar
  3. Ratanatharathorn V, Ayash L, Lazarus HM, Fu J, Uberti JP. Chronic graft-versus-host disease: clinical manifestation and therapy. Bone Marrow Transplant. 2001;28(2):121–9.PubMedCrossRefGoogle Scholar
  4. Scheinfeld NS. Dermatological manifestations of graft-versus-host disease. Medscape. 2013;92(3):151–3.Google Scholar

Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of DermatologySUNY Downstate College of MedicineBrooklynUSA
  2. 2.Department of DermatologyWeil Cornell Medical CollegeNew YorkUSA

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