Abstract
Cutaneous manifestations of HIV and AIDS have been described in several cohorts over the past 30 years. This chapter describes clinical presentation, diagnosis, and treatment of cutaneous disorders that are unique or more common in AIDS patients. They can be divided into infectious, inflammatory, and neoplastic diseases. Infectious diseases consist of viral infections, bacterial infections, fungal infections, and parasitic infections. Viral infections include HSV, HPV, VZV, molluscum contagiosum, EBV, and CMV. Bacterial infections include staphylococcal infections, syphilis, bacillary angiomatosis, and mycobacterial infections. Fungal infections include deep cutaneous fungal infections. Parasitic infections include scabies, both common and crusted. Neoplastic disorders include Kaposi Sarcoma, HPV-related anal squamous cell carcinoma, and cutaneous lymphoproliferative disorders, including plasmablastic lymphoma. Inflammatory disorders include eosinophilic pustular folliculitis, also known as Ofuji’s disease, and various drug reactions due to highly active antiretroviral therapy. Without exception, these disorders show more severe clinical presentations, last longer, and show greater resistance to therapy in this patient population than in immunocompetent individuals. In most instances, treating the underlying immunosuppression leads to an improved outcome.
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Castro-Echeverry, E. (2014). Skin Disorders of AIDS Patients. In: Hall, J. (eds) Skin Diseases in the Immunocompromised. Springer, London. https://doi.org/10.1007/978-1-4471-6479-1_2
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DOI: https://doi.org/10.1007/978-1-4471-6479-1_2
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