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Pediatric Critical Care Medicine pp 431–451Cite as

Primary and Secondary Immunodeficiencies

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Abstract

Primary immunodeficiencies are rare disorders that are frequently considered in critically-ill children that are admitted to the intensive care unit with recurrent life-threatening infections. In this chapter, we have briefly reviewed the primary and secondary immunodeficiencies that an intensivist is likely to encounter in the PICU. The immunodeficiencies have been categorized as primary defects of antibody production, combined Immunodeficiencies, primary defects of cellular immunity, complement deficiencies and phagocytic Disorders.

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Authors and Affiliations

  1. Critical Care Medicine, Children’s Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA

    Rajesh K. Aneja MD.

  2. Department of Pediatrics, Riley Hospital for Children at Indiana University Health, 11100 Euclid Ave, Cleveland, OH, 44106, USA

    Alexandre T. Rotta MD, FCCM, FAAP

Authors
  1. Rajesh K. Aneja MD.
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  2. Alexandre T. Rotta MD, FCCM, FAAP
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Correspondence to Rajesh K. Aneja MD. .

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Editors and Affiliations

  1. Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

    Derek S. Wheeler

  2. Div. of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

    Hector R. Wong

  3. MICHR, University of Michigan Medical Scho, Ann Arbor, Michigan, USA

    Thomas P. Shanley

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© 2014 Springer-Verlag London

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Aneja, R.K., Rotta, A.T. (2014). Primary and Secondary Immunodeficiencies. In: Wheeler, D., Wong, H., Shanley, T. (eds) Pediatric Critical Care Medicine. Springer, London. https://doi.org/10.1007/978-1-4471-6416-6_29

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  • DOI: https://doi.org/10.1007/978-1-4471-6416-6_29

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