Abstract
The appropriate therapy for managing esophageal anastomotic leaks is not clearly established. For uncontained leaks, no trials exist demonstrating superiority of esophageal stenting over what is considered to be the gold standard of surgical intervention (surgical repair with a vascularized, pedicled muscle flap and drainage). Esophageal stenting should be reserved to clinical trials, as it remains investigative in nature. Patients who are offered this intervention should be warned of its off-label application and the potential complications associated with it.
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References
Babor R, Talbot M, Tyndal A. Treatment of upper gastrointestinal leaks with a removable, covered, self-expanding metallic stent. Surg Laparosc Endosc Percut Tech. 2009;19(1):e1–4.
Blackmon SH, Santora R, Schwarz P, Barroso A, Dunkin BJ. Utility of removable esophageal covered self-expanding metal stents for leak and fistula management. Ann Thorac Surg. 2010;89(3):931–6; discussion 936–7.
Bona D, Laface L, Bonavina L, Abate E, Schaffer M, Ugenti I, et al. Covered nitinol stents for the treatment of esophageal strictures and leaks. World J Gastroenterol. 2010;16(18):2260–4.
Brangewitz M, Voigtlander T, Helfritz FA, Lankisch TO, Winkler M, Klempnauer J, et al. Endoscopic closure of esophageal intrathoracic leaks: stent versus endoscopic vacuum-assisted closure, a retrospective analysis. Endoscopy. 2013;45(6):433–8.
Cerna M, Kocher M, Valek V, Aujesky R, Neoral C, Andrasina T, et al. Covered biodegradable stent: new therapeutic option for the management of esophageal perforation or anastomotic leak. Cardiovasc Intervent Radiol. 2011;34(6):1267–71.
Dai Y, Chopra SS, Kneif S, Hunerbein M. Management of esophageal anastomotic leaks, perforations, and fistulae with self-expanding plastic stents. J Thorac Cardiovasc Surg. 2011;141(5):1213–7.
David EA, Kim MP, Blackmon SH. Esophageal salvage with removable covered self-expanding metal stents in the setting of intrathoracic esophageal leakage. Am J Surg. 2011;202(6):796–801; discussion 801.
D’Cuhna J, Rueth NM, Groth SS, Maddaus MA, Andrade RS. Esophageal stents for anastomotic leaks and perforations. J Thorac Cardiovasc Surg. 2011;142(1):39–46.
Eloubeidi MA, Lopes TL. Novel removable internally fully covered self-expanding metal esophageal stent: feasibility, technique of removal, and tissue response in humans. Am J Gastroenterol. 2009;104(6):1374–81.
Evrard S, Le Moine O, Lazaraki G, Dormann A, El Nakadi I, Deviere J. Self-expanding plastic stents for benign esophageal lesions. Gastrointest Endosc. 2004;60(6):894–900.
Feith M, Gillen S, Schuster T, Theisen J, Friess H, Gertler R. Healing occurs in most patients that receive endoscopic stents for anastomotic leakage; dislocation remains a problem. Clin Gastroenterol Hepatol. 2011;9(3):202–10.
Fernandez A, Vila JJ, Vasquez C, Gonzalez-Portela C, de la Iglesia M, Lozano M, et al. Self-expanding plastic stents for the treatment of post-operative esophago-jejuno anastomosis leak. A case series study. Rev Esp Enferm Dig. 2010;102(12):704–10.
Freeman RK, Vyverberg A, Ascioti AJ. Esophageal stent placement for the treatment of acute intrathoracic anastomotic leak after esophagectomy. Ann Thorac Surg. 2011;92(1):204–8; discussion 208.
Gelbmann C, Ratiu NL, Rath HC, Rogler G, Lock G, Scholmerich J, et al. Use of self-expandable plastic stents for the treatment of esophageal perforations and symptomatic anastomotic leaks. Endoscopy. 2004;36(8):695–9.
Gubler C, Schneider PM, Bauerfeind P. Complex anastomotic leaks following esophageal resections: the new stent over sponge approach. Dis Esophagus. 2013;26(6):598–602.
Han XW, Li YD, Wu G, Li MH, Ma XX. New covered mushroom-shaped metallic stent for managing anastomotic leak after esophagogastrostomy with a wide gastric tube. Ann Thorac Surg. 2006;82(2):702–6.
Hirdes MMC, Vleggaar FP, Van der Linde K, Willems M, Totte ER, Siersema PD. Esophageal perforation due to removal of partially covered self-expanding metal stents placed for a benign perforation or leak. Endoscopy. 2011;43(2):156–9.
Hunerbein M, Stroszczynski C, Moesta KT, Schlag PM. Treatment of thoracic anastomotic leaks after esophagectomy with self-expanding plastic stents. Ann Surg. 2004;240(5):801–7.
Jiang F, Yu MF, Ren BH, Yin GW, Zhang Q, Xu L. Nasogastric placement of sump tube through the leak for the treatment of esophagogastric anastomotic leak after esophagectomy for esophageal carcinoma. J Surg Res. 2011;171(2):448–51.
Johnsson E, Lundell L, Liedman B. Sealing of esophageal perforation or ruptures with expandable metallic stents: a prospective controlled study on treatment efficacy and limitations. Dis Esophagus. 2005;18(4):262–6.
Kauer WK, Stein HJ, Dittler HJ, Siewert JR. Stent implantation as a treatment option in patients with thoracic anastomotic leaks after esophagectomy. Surg Endosc. 2008;22(1):50–3.
Keeling WB, Miller DL, Lam GT, Kilgo P, Miller JI, Mansour KA, et al. Low mortality after treatment for esophageal perforation: a single-center experience. Ann Thorac Surg. 2010;90:1669–73.
Kim AW, Liptay MJ, Snow N, Donahue P, Warren WH. Utility of silicone esophageal bypass stents in the management of delayed complex esophageal disruptions. Ann Thorac Surg. 2008;85(6):1962–7; discussion 1967.
Kotzampassakis N, Christodoulou M, Krueger T, Demartines N, Vuillemeier H, Cheng C, et al. Esophageal leaks repaired by a muscle onlay approach in the presence of mediastinal sepsis. Ann Thorac Surg. 2009;88(3):966–72.
Langer FB, Schoppmann SF, Prager G, Riegler FM, Zacherl J. Solving the problem of difficult stent removal due to tissue ingrowth in partially uncovered esophageal self-expanding metal stents. Ann Thorac Surg. 2010;89(5):1691–2.
Lee KM, Shin SJ, Hwang JC, Yoo BM, Cheong JY, Lim SG, et al. Proximal-releasing stent insertion under transnasal endoscopic guidance in patients with postoperative esophageal leakage. Gastrointest Endosc. 2010;72(1):180–5.
Leenders BJ, Stronkhorst A, Smulders FJ, Nieuwenhuijzen GA, Gilissen LP. Removable and repositionable covered metal self-expandable stents for leaks after upper gastrointestinal surgery: experiences in a tertiary referral hospital. Surg Endosc. 2013;27(8):2751–9.
Leers JM, Vivaldi C, Schafer H, Bludau M, Brabender J, Lurje G, et al. Endoscopic therapy for esophageal perforation or anastomotic leak with a self-expandable metallic stent. Surg Endosc. 2009;23(10):2258–62.
Lindenmann J, Matzi V, Porubsky C, Anegg U, Sankin O, Gabor S, et al. Self-expandable covered metal tracheal type stent for sealing cervical anastomotic leak after esophagectomy and gastric pull-up: pitfalls and possibilities. Ann Thorac Surg. 2008;85(1):354–6.
Pennathur A, Chang AC, McGrath KM, Steiner G, Alvelo-Rivera M, Awais O, et al. Polyflex expandable stents in the treatment of esophageal disease: initial experience. Ann Thorac Surg. 2008;85(6):1968–72; discussion 1973.
Salminen P, Gullichsen R, Laine S. Use of self-expandable metal stents for the treatment of esophageal perforations and anastomotic leaks. Surg Endosc. 2009;23(7):1526–30.
Schniewind B, Schafmayer C, Voehrs G, Egberts J, von Schoenfels W, Rose T, et al. Endoscopic endoluminal vacuum therapy is superior to other regimens in managing anastomotic leakage after esophagectomy: a comparative retrospective study. Surg Endosc. 2013;27(10):3883–90.
Schubert D, Scheibach H, Kuhn R, Wex C, Weiss G, Eder F, et al. Endoscopic treatment of thoracic esophageal anastomotic leaks by using silicone-covered, self-expanding polyester stents. Gastrointest Endosc. 2005;61(7):891–6.
Schweigert M, Dubecz A, Stadlhuber RJ, Muschweck H, Stein HJ. Risk of stent-related aortic erosion after endoscopic stent insertion for intrathoracic anastomotic leaks after esophagectomy. Ann Thorac Surg. 2011;92(2):513–8.
Tuebergen D, Rijcken E, Mennigen R, Hopkins AM, Senninger N, Bruewer M. Treatment of thoracic esophageal anastomotic leaks and esophageal perforations with endoluminal stents: efficacy and current limitations. J Gastrointest Surg. 2008;12(7):1168–76.
Zisis C, Guillin A, Heyries L, Lienne P, D’Journo XB, Doddoli C, et al. Stent placement in the management of oesophageal leaks. Eur J Cardiothorac Surg. 2008;33(3):451–6.
Kassis ES, Kosinski AS, Ross P, Koppes KE, Donahue JM, Daniel VC. Predictors of anastomotic leak after esophagectomy: an analysis of the Society of Thoracic Surgeons general thoracic database. Ann Thorac Surg. 2013;96(6):1919–26.
Martin LW, Swisher SG, Hofstetter W, Correa AM, Mehran RJ, Rice DC, et al. Intrathoracic leaks following esophagectomy are no longer associated with increased mortality. Ann Surg. 2005;242(3):392–9; discussion 399–402.
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Blackmon, S.H., Gann, L. (2014). Stents for Esophageal Anastomotic Leak. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach, vol 1. Springer, London. https://doi.org/10.1007/978-1-4471-6404-3_33
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DOI: https://doi.org/10.1007/978-1-4471-6404-3_33
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