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Optimal Therapy for Barrett High Grade Dysplasia

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Difficult Decisions in Thoracic Surgery

Part of the book series: Difficult Decisions in Surgery: An Evidence-Based Approach ((DDSURGERY,volume 1))

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Abstract

The management of Barrett’s esophagus with high-grade dysplasia has undergone an evolution from prophylactic esophagectomy to an organ sparing approach based on endoscopic therapies that have emerged over the recent years. Esophagectomy is now reserved only for selected cases of patients with high-grade dysplasia and intramucosal carcinoma in Barrett’s esophagus. This chapter outlines terminology, the appropriate assessment, the management strategy, and the options of therapy for patients with Barrett’s esophagus with high-grade dysplasia.

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Abbreviations

BE:

Barrett’s esophagus

CT:

Computed tomography

EUS:

Endoscopic ultrasound

GI:

Gastrointestinal

HGD:

High-grade dysplasia

IMC:

Intramucosal carcinoma

LNM:

Lymph node metastasis

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Author information

Authors and Affiliations

  1. Department of Gastroenterology, Hepatology, and Nutrition, University of Chicago, 5841 S. Maryland Avenue, MC 4076, Chicago, IL, 60637, USA

    Gabriel D. Lang MD

  2. Section of Gastroenterology, Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, MC #4076, Chicago, IL, 60637-1463, USA

    Vani J. A. Konda MD

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  1. Gabriel D. Lang MD
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Correspondence to Vani J. A. Konda MD .

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Editors and Affiliations

  1. Surgery, University of Chicago, Chicago, Illinois, USA

    Mark K. Ferguson

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Lang, G.D., Konda, V.J.A. (2014). Optimal Therapy for Barrett High Grade Dysplasia. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach, vol 1. Springer, London. https://doi.org/10.1007/978-1-4471-6404-3_22

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