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Perioperative Arrhythmia Prophylaxis for Major Lung Resection

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Difficult Decisions in Thoracic Surgery

Part of the book series: Difficult Decisions in Surgery: An Evidence-Based Approach ((DDSURGERY,volume 1))

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Abstract

Perioperative arrhythmia is one of the most common complications following general thoracic surgery and carries significant morbidity. Although there is no direct cause and effect relationship between development of perioperative supraventricular arrhythmia and other post-operative complications, it has been shown that the development of an arrhythmia is associated with increased length of stay, morbidity, and mortality. The identification of risk factors for perioperative atrial arrhythmias is crucial in order to direct prophylactic measures to the appropriate patients. Amiodarone and diltiazem significantly reduce the rate of postoperative atrial arrhythmias after major lung resection.

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References

  1. Amar D. Prevention and management of perioperative arrhythmias in the thoracic surgical population. Anesthesiol Clin. 2008;26(2):325–35.

    Article  PubMed  Google Scholar 

  2. Amar D, Zhang H, Roistacher N. The incidence and outcome of ventricular arrhythmias after noncardiac thoracic surgery. Anesth Analg. 2002;95:537–43.

    PubMed  Google Scholar 

  3. Roselli EE, Murthy SC, Rice TW, Houghtaling PL, Pierce CD, Karchmer DP, et al. Atrial fibrillation complicating lung cancer resection. J Thorac Cardiovasc Surg. 2005;130:438–44.

    PubMed  Google Scholar 

  4. Hollings DD, Higgins RS, Faber LP, Warren WH, Liptay MJ, Basu S, et al. Age is a strong risk factor for atrial fibrillation after pulmonary lobectomy. Am J Surg. 2010;199(4):558–61.

    Article  PubMed  Google Scholar 

  5. Passman RS, Gingold DS, Amar D, Lloyd-Jones D, Bennett CL, Zhang H, et al. Prediction rule for atrial fibrillation after major noncardiac thoracic surgery. Ann Thorac Surg. 2005;79(5):1698–703.

    Article  PubMed  Google Scholar 

  6. Vaporciyan AA, Correa AM, Rice DC, Roth JA, Smythe WR, Swisher SG, et al. Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients. J Thorac Cardiovasc Surg. 2004;127(3):779–86.

    Article  PubMed  Google Scholar 

  7. Amar D, Roistacher N, Rusch VW, Leung DH, Ginsburg I, Shang G, et al. Effects of diltiazem prophylaxis on the incidence and clinical outcome of atrial arrhythmias after thoracic surgery. J Thorac Cardiovasc Surg. 2000;120:790–8.

    Article  CAS  PubMed  Google Scholar 

  8. Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences(Committee to Develop Guidelines for the Management of Patients with Atrial Fibrillation). Circulation. 2006;114:700–52.

    Article  Google Scholar 

  9. Wu DH, Xu MY, Mao T, Cao H, Wu DJ, Shen YF. Risk factors for intraoperative atrial fibrillation: a retrospective analysis of 10563 lung operations in a single center. Ann Thorac Surg. 2012;94(1):193–7.

    Article  PubMed  Google Scholar 

  10. Amar D, Zhang H, Heerdt PM, Park B, Fleisher M, Thaler HT. Statin use is associated with reduction in atrial fibrillation after noncardiac thoracic surgery independent t of C-reactive protein. Chest. 2005;128(5):3421–7.

    Article  CAS  PubMed  Google Scholar 

  11. Onaitis M, D’Amico T, Zhao Y, O’Brien S, Harpole D. Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database. Ann Thorac Surg. 2010;90(2):368–74.

    Article  PubMed  Google Scholar 

  12. Cardinale D, Colombo A, Sandri MT, Lamantia G, Colombo N, Civelli M, et al. Increase perioperative N-terminal Pro-B-type natriuretic peptide levels predict atrial fibrillation after thoracic surgery for lung cancer. Circulation. 2007;115:1339–44.

    Article  CAS  PubMed  Google Scholar 

  13. Amar D, Zhang H, Leung DH, Roistacher N, Kadish AH. Older age is the strongest predictor of postoperative atrial fibrillation. Anesthesiology. 2002;96:352–6.

    Article  PubMed  Google Scholar 

  14. Rena O, Papalia E, Oliaro A, Cascadio C, Ruffini E, Filosso PL, et al. Supraventricular arrhythmias after resection surgery of the lung. Eur J Cardiothorac Surg. 2001;20:688–93.

    Article  CAS  PubMed  Google Scholar 

  15. Ciriaco P, Mazzone P, Canneto B, Zannini P. Supraventricular arrhythmia following lung resection for non-small cell lung cancer and its treatment with amiodarone. Eur J Cardiothorac Surg. 2000;18:12–6.

    Article  CAS  PubMed  Google Scholar 

  16. Seely AJ, Ivanovic J, Threader J, Al-Hussaini A, Al-Shehab D, Ramsay T, et al. Systematic classification of morbidity and mortality after thoracic surgery. Ann Thorac Surg. 2010;90(3):936–42.

    Article  PubMed  Google Scholar 

  17. Villamizar NR, Darrabie MD, Burfeind WR, Petersen RP, Onaitis MW, Toloza E, et al. Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy. J Thorac Cardiovasc Surg. 2009;138:419–25.

    Article  PubMed  Google Scholar 

  18. Park BJ, Zhang H, Rusch VW, Amar D. Video-assisted thoracic surgery does not reduce the incidence of postoperative atrial fibrillation after pulmonary lobectomy. J Thorac Cardiovasc Surg. 2007;133(3):775–9.

    Article  PubMed  Google Scholar 

  19. Whitson BA, Groth SS, Duval SJ, Swanson SJ, Maddaus MA. Surgery for early-stage non-small cell lung cancer: a systematic review of the video assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy. Ann Thorac Surg. 2008;86:2008–18.

    Article  PubMed  Google Scholar 

  20. Tisdale JE, Wroblewski HA, Wall DS, Rieger KM, Hammoud ZT, Young JV, et al. A randomized trial evaluating amiodarone for prevention of atrial fibrillation after pulmonary resection. Ann Thorac Surg. 2009;88(3):886–93.

    Article  PubMed  Google Scholar 

  21. Riber LP, Christensen TD, Jensen HK, Hoejsgaard A, Pilegaard HK. Amiodarone significantly decreases atrial fibrillation in patients undergoing surgery for lung cancer. Ann Thorac Surg. 2012;94(2):339–44.

    Article  PubMed  Google Scholar 

  22. Lanza LA, Visbal AI, DeValeria PA, Zinsmeister AR, Diehl NN, Trastek VF. Low-dose oral amiodarone prophylaxis reduces atrial fibrillation after pulmonary resection. Ann Thorac Surg. 2003;75(1):223–30.

    Article  PubMed  Google Scholar 

  23. Khalil MA, Al-Agaty AE, Ali WG, Abdel Azeem MS. A comparative study between amiodarone and magnesium sulfate as antiarrhythmic agents for prophylaxis against atrial fibrillation following lobectomy. J Anesth. 2013;27(1):56–61.

    Article  PubMed  Google Scholar 

  24. Sedrakyan A, Treasure T, Browne J, Krumholz H, Sharpin C, van der Meulen J. Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials. J Thorac Cardiovasc Surg. 2005;129(5):997–1005.

    Article  CAS  PubMed  Google Scholar 

  25. Dunning J, Treasure T, Versteegh M, Nashef SA. Guidelines on the prevention and management of de novo atrial fibrillation after cardiac and thoracic surgery. Eur J Cardiothorac Surg. 2006;30(6):852–72.

    Article  PubMed  Google Scholar 

  26. Shrivastava V, Nyawo B, Dunning J, Morritt G. Is there a role for prophylaxis against atrial fibrillation for patients undergoing lung surgery? Interact Cardiovasc Thorac Surg. 2004;3(4):656–62.

    Article  PubMed  Google Scholar 

  27. Oka T, Ozawa Y, Ohkubo Y. Thoracic epidural bupivacaine attenuates supraventricular tachyarrhythmias after pulmonary resection. Anesth Analg. 2001;93(2):253–9.

    CAS  PubMed  Google Scholar 

  28. Simeoforidou M, Vretzakis G, Bareka M, Chantzi E, Flossos A, Giannoukas A, et al. Thoracic epidural analgesia with levobupivacaine for 6 postoperative days attenuates sympathetic activation after thoracic surgery. J Cardiothorac Vasc Anesth. 2011;25(5):817–23.

    Article  CAS  PubMed  Google Scholar 

  29. Jiang Z, Dai JQ, Shi C, Zeng WS, Jiang RC, Tu WF. Influence of patient-controlled i.v. analgesia with opioids on supraventricular arrhythmias after pulmonary resection. Br J Anaesth. 2009;103(3):364–8.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Thoracic Surgery, Henry Ford Hospital, K-14, 2799 West Grand Blvd, Detroit, MI, 48202, USA

    Arielle Hodari MD & Zane Hammoud MD, FACS

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  1. Arielle Hodari MD
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  2. Zane Hammoud MD, FACS
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Correspondence to Arielle Hodari MD .

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Editors and Affiliations

  1. Surgery, University of Chicago, Chicago, Illinois, USA

    Mark K. Ferguson

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© 2014 Springer-Verlag London

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Hodari, A., Hammoud, Z. (2014). Perioperative Arrhythmia Prophylaxis for Major Lung Resection. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach, vol 1. Springer, London. https://doi.org/10.1007/978-1-4471-6404-3_10

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  • DOI: https://doi.org/10.1007/978-1-4471-6404-3_10

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-6403-6

  • Online ISBN: 978-1-4471-6404-3

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