Abstract
Thymus is a specialized organ of the immune system, responsible for the maturation, differention, and education of T lymphocytes. While nonvascular implantation of thymic tissues may cause ischemia and disruption of the normal microarchitecture of the gland, vascular transplantation gives no harm to the microarchitecture. A new method of thymus transplantation is introduced, in which the graft is directly connected with the recipient’s vascular system which might be used both in euthymic rats and congenitally athymic nude rats. This novel model is a unique vascular transplantation to evaluate the viability of vascularized thymus transplantation, immunotransplantation, and maturation of the T cells.
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Ortak, T. (2015). Vascular Thymus Transplantation Model. In: Siemionow, M. (eds) Plastic and Reconstructive Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-6335-0_24
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DOI: https://doi.org/10.1007/978-1-4471-6335-0_24
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