Abstract
Medical imaging has progressively grown into a variety of different imaging modalities and technologies that allow for the visualization and analysis of the human body for diagnosis, and for monitoring of a variety of diseases and for the assessment of treatments or therapeutic interventions efficacy. Technical innovations have led to the development of multimodal, or hybrid, imaging devices that combine different imaging methods in a simultaneous or sequential way. The underlying idea of hybrid imaging devices is to combine functional and metabolic information (positron emission tomography, PET, or single-photon positron emission tomography, SPECT) together with anatomical and morphological characterization (x-ray computed tomography, CT, or magnetic resonance imaging, MRI). The first hybrid device applied for clinical use was the combination of SPECT with CT. Nowadays PET/CT plays the role of an important diagnostic tool in clinical routine. Concurrently, the concepts for combining PET with MRI were explored, but only recently a first generation of hybrid PET/MRI scanners has been developed and tested in clinical applications. The first clinical data obtained from the emerging PET/MRI imaging technique are showing their potential and defining their role in clinical routine, and it may supersede PET/CT in many applications and practical aspects in the future.
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García Juan, D., Trombella, S., Ratib, O. (2014). Hybrid Imaging: From Anatomy to Function. In: Magnenat-Thalmann, N., Ratib, O., Choi, H. (eds) 3D Multiscale Physiological Human. Springer, London. https://doi.org/10.1007/978-1-4471-6275-9_3
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