Abstract
Neurodegenerative diseases, such as Alzheimer’s disease and related conditions, currently represent a major public healthcare problem. Attention disorders are often present and disabling in these patients, but frequently remain undiagnosed. The present chapter focuses in particular on visual neglect and monitoring deficits.
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References
Alladi S, Xuereb J, Bak T, Nestor P, Knibb J, Patterson K, Hodges JR. Focal cortical presentations of Alzheimer’s disease. Brain. 2007;130:2636–45.
Andrade K, Samri D, Sarazin M, Cruz De Souza L, Cohen L, Thiebaut de Schotten M, Dubois B, Bartolomeo P. Visual neglect in posterior cortical atrophy. BMC Neurol. 2010;10:68.
Andrade K, Kas A, Valabrègue R, Samri D, Sarazin M, Habert MO, Dubois B, Bartolomeo P. Visuospatial deficits in posterior cortical atrophy: structural and functional correlates. J Neurol Neurosurg Psychiatry. 2012;83:860–3.
Balota DA, Faust ME. Attention in dementia of the Alzheimer’s type. In: Boller F, Grafman J, editors. Handbook of neuropsychology. 2nd ed. Amsterdam: Elsevier Science Publishers; 2001. p. 51–80.
Bartolomeo P. The quest for the ‘critical lesion site’ in cognitive deficits: problems and perspectives. Cortex. 2011;47:1010–2.
Bartolomeo P, Dalla Barba G, Boissé MT, Bachoud-Lévi AC, Degos JD, Boller F. Right-side neglect in Alzheimer’s disease. Neurology. 1998;51:1207–9.
Bartolomeo P, Migliaccio R. Disorders of attentional processes. In: Husain M, Schott J, editors. Oxford textbook of cognitive neurology and dementia. Oxford: Oxford University Press (in press).
Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. Forecasting the global burden of Alzheimer’s disease. Alzheimers Dement. 2007;3:186–91.
Couette M, Bachoud-Lévi AC, Brugières P, Siéroff E, Bartolomeo P. Orienting of spatial attention in Huntington’s disease. Neuropsychologia. 2008;46:1391–400.
Cristinzio C, Bononi M, Piacentini S, Albanese A, Bartolomeo P. Attentional networks in Parkinson’s disease. Behavioural Neurology. 2013;27(4):495–500.
D’Erme P, Bartolomeo P, Masullo C. Alzheimer's disease presenting with visuo-spatial disorders. Ital J Neurol Sci. 1991 (abstract);12:117.
Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci U S A. 2006;103:13848–53.
Danckert J, Maruff P, Crowe S, Currie J. Inhibitory processes in covert orienting in patients with Alzheimer’s disease. Neuropsychology. 1998;12:225–41.
Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger-Gateau P, Cummings J, Delacourte A, Galasko D, Gauthier S, Jicha G, Meguro K, O’Brien J, Pasquier F, Robert P, Rossor M, Salloway S, Stern Y, Visser PJ, Scheltens P. Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS-ADRDA criteria. Lancet Neurol. 2007;6:734–46.
Filippi M, Agosta F, Scola E, Canu E, Magnani G, Marcone A, Valsasina P, Caso F, Copetti M, Comi G, Cappa SF, Falini A. Functional network connectivity in the behavioral variant of frontotemporal dementia. Cortex. 2013;49(9):2389–401.
Fox MD, Corbetta M, Snyder AZ, Vincent JL, Raichle ME. Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci U S A. 2006;103:10046–51.
Frisoni GB, Pievani M, Testa C, Sabattoli F, Bresciani L, Bonetti M, Beltramello A, Hayashi KM, Toga AW, Thompson PM. The topography of grey matter involvement in early and late onset Alzheimer’s disease. Brain. 2007;130:720–30.
Georgiou-Karistianis N, Farrow M, Wilson-Ching M, Churchyard A, Bradshaw JL, Sheppard DM. Deficits in selective attention in symptomatic Huntington disease: assessment using an attentional blink paradigm. Cogn Behav Neurol. 2012;25:1–6.
Husain M, Nachev P. Space and the parietal cortex. Trends Cogn Sci. 2007;11:30–66.
Ishiai S, Koyama Y, Seki K, Orimo S, Sodeyama N, Ozawa E, Lee EY, Takahashi M, Watabiki S, Okiyama R, Ohtake T, Hiroki M. Unilateral spatial neglect in AD: significance of line bisection performance. Neurology. 2000;55:364–70.
Mendez MF, Cherrier MM, Cymerman JS. Hemispatial neglect on visual search tasks in Alzheimer’s disease. Neuropsychiatry Neuropsychol Behav Neurol. 1997;10:203–8.
Migliaccio R, Agosta F, Rascovsky K, Karydas A, Bonasera S, Rabinovici GD, Miller BL, Gorno-Tempini ML. Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum. Neurology. 2009;73:1571–8.
Migliaccio R, Agosta F, Toba MN, Samri D, Corlier F, de Souza LC, Chupin M, Sharman M, Gorno-Tempini ML, Dubois B, Filippi M, Bartolomeo P. Brain networks in posterior cortical atrophy: a single case tractography study and literature review. Cortex. 2012a;48:1298–309.
Migliaccio R, Agosta F, Scola E, Magnani G, Cappa SF, Pagani E, Canu E, Comi G, Falini A, Gorno-Tempini ML, Bartolomeo P, Filippi M. Ventral and dorsal visual streams in posterior cortical atrophy: a DT MRI study. Neurobiol Aging. 2012b;33:2572–84.
Parasuraman R, Greenwood PM, Haxby JV, Grady CL. Visuospatial attention dementia of the Alzheimer type. Brain. 1992;115(Pt 3):711–33.
Possin KL. Visual spatial cognition in neurodegenerative disease. Neurocase. 2010;16:466–87.
Rafal RD, Posner MI, Friedman JH, Inhoff AW, Bernstein E. Orienting of visual attention in progressive supranuclear palsy. Brain. 1988;111:267–80.
Rosen HJ, Gorno-Tempini ML, Goldman WP, Perry RJ, Schuff N, Weiner M, Feiwell R, Kramer JH, Miller BL. Patterns of brain atrophy in frontotemporal dementia and semantic dementia. Neurology. 2002;58:198–208.
Schroeter ML, Raczka K, Neumann J, von Cramon DY. Neural networks in frontotemporal dementia – a meta-analysis. Neurobiol Aging. 2008;29:418–26.
Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci. 2007;27:2349–56.
Seeley WW, Crawford R, Rascovsky K, Kramer JH, Weiner M, Miller BL, Gorno-Tempini ML. Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia. Arch Neurol. 2008;65:249–55.
Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD. Neurodegenerative diseases target large-scale human brain networks. Neuron. 2009;62:42–52.
Silveri MC, Ciccarelli N, Cappa A. Unilateral spatial neglect in degenerative brain pathology. Neuropsychology. 2011;25:554–66.
Venneri A, Pentore R, Cotticelli B, Della Sala S. Unilateral spatial neglect in the late stage of Alzheimer’s disease. Cortex. 1998;34:743–52.
von Gunten A, Bouras C, Kovari E, Giannakopoulos P, Hof PR. Neural substrates of cognitive and behavioral deficits in atypical Alzheimer’s disease. Brain Res Rev. 2006;51:176–211.
Weintraub S, Daffner KR, Ahern GL, Price BH, Mesulam MM. Right sided hemispatial neglect and bilateral cerebral lesions. J Neurol Neurosurg Psychiatry. 1996;60:342–4.
Wright MJ, Burns RJ, Geffen GM, Geffen LB. Covert orientation of visual attention in Parkinson’s disease: an impairment in the maintenance of attention. Neuropsychologia. 1990;28:151–9.
Further Reading
Balota DA, Faust ME. Attention in dementia of the Alzheimer’s type. In: Boller F, Grafman J, editors. Handbook of neuropsychology. 2nd ed. Amsterdam: Elsevier Science Publishers; 2001. p. 51–80.
Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD. Neurodegenerative diseases target large-scale human brain networks. Neuron. 2009;62(1):42–52.
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Bartolomeo, P. (2014). Attention Disorders in Neurodegenerative Conditions. In: Attention Disorders After Right Brain Damage. Springer, London. https://doi.org/10.1007/978-1-4471-5649-9_8
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DOI: https://doi.org/10.1007/978-1-4471-5649-9_8
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