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Chronic Kidney Disease: Epidemiology and Causes

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Practical Nephrology
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Abstract

In this chapter we consider the practical role of CKD epidemiology, especially how it helps understand the burden of CKD and RRT and how we can appreciate the best targets for prevention and treatment of our patients with kidney disease.

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References

  1. Feest TG, Harrison P. Simulation model for planning renal services. BMJ. 1992;305(6860):1018.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Levey AS, Stevens LA, Coresh J. Conceptual model of CKD: applications and implications. Am J Kidney Dis. 2009;53(3 Suppl 3):S4–16.

    Article  PubMed  Google Scholar 

  3. Hallan SI, Orth SR. The KDOQI 2002 classification of chronic kidney disease: for whom the bell tolls. Nephrol Dial Transplant. 2010;25(9):2832–6.

    Article  PubMed  Google Scholar 

  4. Levey AS, de Jong PE, Coresh J, El Nahas M, Astor BC, Matsushita K, et al. The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report. Kidney Int. 2011;80(1):17–28.

    Article  PubMed  Google Scholar 

  5. Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis. 2003;41(1):1–12.

    Article  PubMed  Google Scholar 

  6. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130(6):461–70.

    Article  CAS  PubMed  Google Scholar 

  7. Froissart M, Rossert J, Jacquot C, Paillard M, Houillier P. Predictive performance of the modification of diet in renal disease and Cockcroft-Gault equations for estimating renal function. J Am Soc Nephrol. 2005;16(3):763–73.

    Article  PubMed  Google Scholar 

  8. Matsushita K, Mahmoodi BK, Woodward M, Emberson JR, Jafar TH, Jee SH, et al. Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA. 2012;307(18):1941–51.

    Article  CAS  PubMed  Google Scholar 

  9. Hallan SI, Coresh J, Astor BC, Asberg A, Powe NR, Romundstad S, et al. International comparison of the relationship of chronic kidney disease prevalence and ESRD risk. J Am Soc Nephrol. 2006;17(8):2275–84.

    Article  PubMed  Google Scholar 

  10. Group TEIS. Geographic, ethnic, age-related and temporal variation in the incidence of end-stage renal disease in Europe, Canada and the Asia-Pacific region, 1998–2002. Nephrol Dial Transplant. 2002;21(8):2178–83.

    Google Scholar 

  11. Matsushita K, Ballew SH, Astor BC, Jong PE, Gansevoort RT, Hemmelgarn BR, et al. Cohort profile: the chronic kidney disease prognosis consortium. Int J Epidemiol. 2013;42(6):1660–8. doi:10.1093/ije/dys173.

  12. Xue JL, Daniels F, Star RA, Kimmel PL, Eggers PW, Molitoris BA, Himmelfarb J, Collins AJ. Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001. J Am Soc Nephrol. 2006;17(4):1135–42.

    Article  PubMed  Google Scholar 

  13. Prescott GJ, Metcalfe W, Baharani J, Khan IH, Simpson K, Smith WC, MacLeod AM. A prospective national study of acute renal failure treated with RRT: incidence, aetiology and outcomes. Nephrol Dial Transplant. 2007;22(9):2513–9.

    Article  PubMed  Google Scholar 

  14. Coca SG, Yusuf B, Shlipak MG, Garg AX, Parikh CR. Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis. 2009;53(6):961–73. doi:10.1053/j.ajkd.2008.11.034.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Minutolo R, De Nicola L, Mazzaglia G, Postorino M, Cricelli C, Mantovani LG, Conte G, Cianciaruso B. Detection and awareness of moderate to advanced CKD by primary care practitioners: a cross-sectional study from Italy. Am J Kidney Dis. 2008;52(3):444–53. doi:10.1053/j.ajkd.2008.03.002.

    Article  PubMed  Google Scholar 

  16. Silverwood RJ, Pierce M, Hardy R, Sattar N, Whincup P, Ferro C, Savage C, Kuh D, Nitsch D. Low birth weight, later renal function, and the roles of adulthood blood pressure, diabetes, and obesity in a British birth cohort. Kidney Int. 2013;84(6):1262–70. doi:10.1038/ki.2013.223.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  17. Perneger TV, Whelton PK, Klag MJ, Rossiter KA. Diagnosis of hypertensive end-stage renal disease: effect of patient’s race. Am J Epidemiol. 1995;141(1):10–5.

    Google Scholar 

  18. Giles PD, Fitzmaurice DA. Formula estimation of glomerular filtration rate: have we gone wrong. BMJ. 2007;334(7605):1198–200.

    Google Scholar 

  19. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for evaluation and management of chronic kidney disease. Kidney Int. 2013;3(Suppl):1–150.

    Google Scholar 

  20. Landray MJ, Wheeler DC, Lip GY, Newman DJ, Blann AD, McGlynn FJ, Ball S, Townend JN, Baigent C. Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study. Am J Kidney Dis. 2004;43(2):244–53.

    Google Scholar 

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Correspondence to Dorothea Nitsch MD, MSc .

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© 2014 Springer-Verlag London

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Nitsch, D. (2014). Chronic Kidney Disease: Epidemiology and Causes. In: Harber, M. (eds) Practical Nephrology. Springer, London. https://doi.org/10.1007/978-1-4471-5547-8_47

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  • DOI: https://doi.org/10.1007/978-1-4471-5547-8_47

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5546-1

  • Online ISBN: 978-1-4471-5547-8

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