Abstract
The majority of individuals diagnosed with Marfan syndrome have a mutation in the fibrillin 1 (FBN1) gene located on chromosome 15. This genetic change will have either been inherited (75 % chance) from one of the parents or the mutation will have arisen as result of a new or “de novo” change (25 %). Discussions with health care professionals trained in genetics, a genetic counsellor or clinical geneticist specialising in cardiac conditions would be recommended so that individuals can fully understand their options prior to planning a family.
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Sage, K. (2016). Reproductive Decisions. In: Child, A. (eds) Diagnosis and Management of Marfan Syndrome. Springer, London. https://doi.org/10.1007/978-1-4471-5442-6_23
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DOI: https://doi.org/10.1007/978-1-4471-5442-6_23
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