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Introduction to Evolutionary Genomics pp 125–154Cite as

Natural Selection

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Part of the book series: Computational Biology ((COBO,volume 17))

Abstract

Basic concept of natural selection is first discussed, and purifying (negative) selection is shown to be much more prevalent than positive selection. Natural selection on haploids and diploids is discussed under both large populations and small populations. Natural selection at the genomic level is then described, covering various topics such as gain and loss of genes and purifying selection at synonymous sites and at noncoding regions. Positive selection for ape and human genes and detection of positive selection through genome-wide searches are also discussed.

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  1. Division of Population Genetics, National Institute of Genetics (NIG), Mishima, Shizuoka, Japan

    Naruya Saitou

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  1. Naruya Saitou
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Saitou, N. (2013). Natural Selection. In: Introduction to Evolutionary Genomics. Computational Biology, vol 17. Springer, London. https://doi.org/10.1007/978-1-4471-5304-7_5

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  • DOI: https://doi.org/10.1007/978-1-4471-5304-7_5

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