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Physiological Assessment of Coronary Stenoses and the Microcirculation pp 185–192Cite as

Measurements of Microcirculatory Resistance

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Abstract

The coronary microvasculature is an extremely dynamic system that responds to multiple physiological conditions in order to maintain adequate myocardial perfusion [1, 2]. Modulation of microcirculatory resistance plays a key role in this regulatory process. The underling pathophysiology and adaptive mechanisms of the microcirculation are fully described in other chapters in this book. In patients with ischemic heart disease (IHD), obstructive lesions in epicardial vessels are not a prerequisite for myocardial ischemia [3], which may arise from microcirculatory dysfunction (MCD). It has been shown that MCD is an independent predictor of poorer clinical outcomes in different clinical scenarios [4, 5] and, therefore, outlining its presence in such clinical situations might be important.

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Authors and Affiliations

  1. Instituto Cardiovascular, Hospital Clínico San Carlos, Calle Prof Martin Lagos, Madrid, 28040, Spain

    Nicola Ryan, Mauro Echavarría-Pinto, Alicia Quirós, Hernán Mejía-Rentería, María Del Trigo, Pilar Jiménez-Quevedo & Javier Escaned

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  1. Nicola Ryan
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Editors and Affiliations

  1. Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain

    Javier Escaned

  2. Imperial College London, London, United Kingdom

    Justin Davies

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Ryan, N. et al. (2017). Measurements of Microcirculatory Resistance. In: Escaned, J., Davies, J. (eds) Physiological Assessment of Coronary Stenoses and the Microcirculation. Springer, London. https://doi.org/10.1007/978-1-4471-5245-3_13

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  • DOI: https://doi.org/10.1007/978-1-4471-5245-3_13

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  • Print ISBN: 978-1-4471-5244-6

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