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Transcatheter Aortic Valve Replacement

  • Chapter
Aortic Stenosis

Abstract

Aortic stenosis is a common disease with a prevalence of approximately 5 % in elderly patients. The population of people in the United States older than 65 is expected to increase from 40 million in 2010 to nearly 80 million by 2050. With this demographic shift, the burden of valvular heart disease will increase as well. Surgical aortic valve replacement (SAVR) has long been the standard of care for the treatment of severe aortic stenosis. Multiple studies however, have documented that nearly 40 % of elderly patients with severe symptomatic aortic stenosis do not undergo surgery; mainly because of advanced age and comorbidities. This unmet clinical need was the impetus for the development of transcatheter aortic valve replacement (TAVR). Since Cribier treated the first patient in 2002, great strides have been made in the technology and TAVR has become the standard of care for appropriately selected inoperable patients and it is an alternative to surgery for high-risk patients.

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  1. Department of Cardiovascular Medicine, Beaumont Health, Oakland University/William Beaumont School of Medicine, Royal Oak, MI, USA

    George S. Hanzel MD

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Correspondence to George S. Hanzel MD .

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  1. Interventional Cardiology Research, Beaumont Health System, Royal Oak, Michigan, USA

    Amr E. Abbas

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Hanzel, G.S. (2015). Transcatheter Aortic Valve Replacement. In: Abbas, A. (eds) Aortic Stenosis. Springer, London. https://doi.org/10.1007/978-1-4471-5242-2_15

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