Abstract
Vasovagal reactions are common in patients undergoing percutaneous coronary intervention under local anaesthetic, and most commonly present with a low heart rate and/or peripheral vasodilatation coupled with some degree of transient cerebral dysfunction, ranging from lightheadedness to a brief loss of consciousness. While normally brief, and often self-limiting, prompt recognition and treatment – and where possible prevention – of vasovagal reactions is an important skill for all interventional cardiologists. Several prophylactic measures such as the avoidance of dehydration, the reduction of pain perception with adequate analgesia and conscious sedation, the utilization of closure devices after removal of femoral arterial sheath and the intra-arterial administration of vasodilators in the radial artery approach, may be of great value.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Juergens CP, Leung DY, Crozier JA, Wong AM, Robinson JT, Lo S, et al. Patient tolerance and resource utilization associated with an arterial closure versus an external compression device after percutaneous coronary intervention. Catheter Cardiovasc Interv. 2004;63:166–70.
Mager A, Strasberg B, Rechavia E, Birnbaum Y, Mazur A, Yativ N, Sclarovscky S. Clinical significance and predisposing factors to symptomatic bradycardia and hypotension after percutaneous transluminal coronary angioplasty. Am J Cardiol. 1994;74:1085–8.
Fulton TR, Peet GI, McGrath MA, Hilton JD, Smith RE, Sigurdsson AF, Forrest GQ. Effects of 3 analgesic regimens on the perception of pain after removal of femoral artery sheaths. Am J Crit Care. 2000;9:125–9.
Romme JJ, van Dijk N, Boer KR, Dekker LR, Stam J, Reitsma JB, Wieling W. Influence of age and gender on the occurrence and presentation of reflex syncope. Clin Auton Res. 2008;18:127–33.
Epstein AE, DiMarco JP, Ellenbogen KA, Estes 3rd NA, Freedman RA, Gettes LS, et al. ACC/AHA/HRS, 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pacemakers and antiarrhythmia devices): developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol. 2008;51:e1–62.
van Lieshout JJ, Wieling W, Karemaker JM, Eckberg DL. The vasovagal response. Clin Sci (Lond). 1991;81:575–86.
Wallin BG, Sundlof G. Sympathetic outflow to muscles during vasovagal syncope. J Auton Nerv Syst. 1982;6:287–91.
Ziegler MG, Echon C, Wilner KD, Specho P, Lake CR, McCutchen JA. Sympathetic nervous withdrawal in the vasodepressor (vasovagal) reaction. J Auton Nerv Syst. 1986;17:273–8.
Tavakol M, Ashraf S, Brener SJ. Risks and complications of coronary angiography: a comprehensive review. Glob J Health Sci. 2012;4:65–93.
Landau C, Lange RA, Glamann DB, Willard JE, Hillis LD. Vasovagal reactions in the cardiac catheterization laboratory. Am J Cardiol. 1994;73:95–7.
Kiat Ang C, Leung DY, Lo S, French JK, Juergens CP. Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. Int J Cardiol. 2007;116:321–6.
Hetherington SL, Adam Z, Morley R, de Belder MA, Hall JA, Muir DF, et al. Primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: changing patterns of vascular access, radial versus femoral artery. Heart. 2009;95:1612–8.
Jolly SS, Amlani S, Hamon M, Yusuf S, Mehta SR. Radial versus femoral access for coronary angiography or intervention and the impact on major bleeding and ischemic events: a systematic review and meta-analysis of randomized trials. Am Heart J. 2009;157:132–40.
Eichhöfer J, Horlick E, Ivanov J, Seidelin PH, Ross JR, Ing D, et al. Decreased complication rates using the transradial compared to the transfemoral approach in percutaneous coronary intervention in the era of routine stenting and glycoprotein platelet IIb/IIIa inhibitor use: a large single-center experience. Am Heart J. 2008;156:864–70.
Kiemeneij F, Laarman GJ, Odekerken D, Slagboom T, van der Wieken R. A randomized comparison of percutaneous transluminal coronary angioplasty by the radial, brachial and femoral approaches: the access study. J Am Coll Cardiol. 1997;29:1269–75.
Freestone B, Nolan J. Transradial cardiac procedures: the state of the art. Heart. 2010;96:883–91.
Deftereos S, Giannopoulos G, Raisakis K, Hahalis G, Kaoukis A, Kossyvakis C, et al. Moderate procedural sedation and opioid analgesia during transradial coronary interventions to prevent spasm: a prospective randomized study. JACC Cardiovasc Interv. 2013;6:267–73.
Saito S, Tanaka S, Hiroe Y, Miyashita Y, Takahashi S, Satake S, et al. Usefulness of hydrophilic coating on arterial sheath introducer in transradial coronary intervention. Catheter Cardiovasc Interv. 2002;56:328–32.
Koga S, Ikeda S, Futagawa K, Sonoda K, Yoshitake T, Miyahara Y, Kohno S, et al. The use of a hydrophilic-coated catheter during transradial cardiac catheterization is associated with a low incidence of radial artery spasm. Int J Cardiol. 2004;96:255–8.
Caussin C, Gharbi M, Durier C, Ghostine S, Pesenti Rossi D, Rahal S, et al. Reduction in spasm with a long hydrophylic transradial sheath. Catheter Cardiovasc Interv. 2010;76:668–72.
Rathore S, Stables RH, Pauriah M, Hakeem A, Mills JD, Palmer ND, et al. Impact of length and hydrophilic coating of the introducer sheath on radial artery spasm during transradial coronary intervention: a randomized study. JACC Cardiovasc Interv. 2010;3:475–83.
Kiemeneij F, Vajifdar BU, Eccleshall SC, Laarman G, Slagboom T, van der Wieken R. Evaluation of a spasmolytic cocktail to prevent radial artery spasm during coronary procedures. Catheter Cardiovasc Interv. 2003;58:281–4.
Varenne O, Jégou A, Cohen R, Empana JP, Salengro E, Ohanessian A, et al. Prevention of arterial spasm during percutaneous coronary interventions through radial artery: the SPASM study. Catheter Cardiovasc Interv. 2006;68:231–5.
Santini M, Ammirati F, Colivicchi F, Gentilucci G, Guido V. The effect of atropine in vasovagal syncope induced by head-up tilt testing. Eur Heart J. 1999;20:1745–51.
Kern MJ. The cardiac catheterization handbook. 5th ed. Philadelphia: Elsevier; 2011.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer-Verlag London
About this chapter
Cite this chapter
Kalogeropoulos, A.S., Lindsay, A. (2016). Preventing and Treating Vasovagal Reactions. In: Lindsay, A., Chitkara, K., Di Mario, C. (eds) Complications of Percutaneous Coronary Intervention. Springer, London. https://doi.org/10.1007/978-1-4471-4959-0_1
Download citation
DOI: https://doi.org/10.1007/978-1-4471-4959-0_1
Publisher Name: Springer, London
Print ISBN: 978-1-4471-4958-3
Online ISBN: 978-1-4471-4959-0
eBook Packages: MedicineMedicine (R0)