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Reproductive Surgery in Assisted Conception pp 223–228Cite as

Local Endometrial Trauma: A Treatment Strategy to Improve Implantation Rates

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Abstract

Implantation continues to be a rate-limiting step, despite the various advances and the increasing success rates of assisted conception treatment in recent years. For implantation to occur a blastocyst must attach to and invade the endometrium under the influence of both oestrogen and progesterone. Many factors can affect an embryo’s implantation potential, including sperm and oocyte quality in addition to iatrogenic factors such as laboratory conditions and embryo transfer technique. In addition, many conditions of the uterine cavity may influence the ability of the embryo to implant. Although the role of the endometrium in implantation is complex and not fully understood, it is thought that inducing controlled endometrial trauma can increase endometrial receptivity and this novel approach is examined in this chapter.

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Author information

Authors and Affiliations

  1. Department of Reproductive Medicine and Surgery, Rotunda IVF, Rotunda Hospital, Parnell Square, Dublin 1, UK

    Carol Coughlan MD, MRCOG, MRCPI

Authors
  1. Carol Coughlan MD, MRCOG, MRCPI
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Corresponding author

Correspondence to Carol Coughlan MD, MRCOG, MRCPI .

Editor information

Editors and Affiliations

  1. Reproductive Medicine and Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom

    Mostafa Metwally

  2. Obstetrics and Gynaecology, Chinese University of Hong Kong, Hong Kong, China

    Tin-Chiu Li

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Coughlan, C. (2015). Local Endometrial Trauma: A Treatment Strategy to Improve Implantation Rates. In: Metwally, M., Li, TC. (eds) Reproductive Surgery in Assisted Conception. Springer, London. https://doi.org/10.1007/978-1-4471-4953-8_22

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  • DOI: https://doi.org/10.1007/978-1-4471-4953-8_22

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4952-1

  • Online ISBN: 978-1-4471-4953-8

  • eBook Packages: MedicineMedicine (R0)

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