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Closure of Post-AMI Ventricular Septal Defect

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Abstract

Ventricular septal defect (VSD) is a rare but deadly mechanical complication of acute myocardial infarction (AMI). Although significantly lower than with conservative management, in-hospital mortality after surgery remains as high as 47%, and dehiscence of the patch requiring a second operation is not infrequent because the sutures may teat out of the friable support around the defect. In today's era of percutaneous interventions, percutaneous closure is considered a valid alternative to surgical repair in patients with small to medium VSDs, since the occlusion device may provide a definitive treatment. Two-dimensional TTE/TEE color Doppler provides the most rapid diagnosis by demonstration of a discontinuity in the ventricular septum with left-to-right shunt. 3D TEE appears to be a very valuable tool in showing the defect as it anatomically is: a hole through the septum. In this chapter we describe 3D TEE anatomy of ventricular septum, 3D TEE imaging of post-AMI VSDs, and the current use of 3D TEE during percutaneous closure with catheter-based devices.

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Suggested Reading

  • Benton JP, Barker KS. Transcatheter closure of ventricular septal defect: a nonsurgical approach to the care of the patient with acute ventricular septal rupture. Heart Lung. 1992;21:356–64.

    PubMed  CAS  Google Scholar 

  • Cooley DA, Belmonte BA, Zeis LB, Schnur S. Surgical repair of ruptured interventricular septum following acute myocardial infarction. Surgery. 1957;41:930–7. The first report of surgical repair for postinfarction ventricular septal rupture.

    PubMed  CAS  Google Scholar 

  • Cox FF, Morshuis WJ, Plokker T, Kelder JC, van Swieten HA, de la Brutel Riviere A A, et al. Early mortality after surgical repair of postinfarction ventricular septal rupture: importance of rupture location. Ann Thorac Surg. 1996;61:1752–8.

    Article  PubMed  CAS  Google Scholar 

  • Crenshaw BS, Granger CB, Birnbaum Y, Pieper KS, Morris DC, Kleiman NS, et al. Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. Circulation. 2000;101:27–32.

    Article  PubMed  CAS  Google Scholar 

  • Daggett WM, Guyton RA, Mundth ED, Buckley MJ, McEnany MT, Gold HK, et al. Surgery for post-myocardial infarct ventricular septal defect. Ann Surg. 1977;186:260–71. Sets out the principles of surgical repair.

    Article  PubMed  CAS  Google Scholar 

  • Dalrymple-Hay MJR, Monro JL, Livesey SA, Lamb RK. Postinfarction ventricular septal rupture: the Wessex experience. Semin Thorac Cardiovasc Surg. 1998;10:111–6. The largest reported single-centre experience of the condition and its surgical treatment.

    PubMed  CAS  Google Scholar 

  • Deja MA, Szostek J, Widenka K, Szafron B, Spyt TJ, Hickey MS, Sosnowski AW. Post infarction ventricular septal defect – can we do better? Eur J Cardiothoracic Surg. 2000;18:194–201. Provides long-term followup data for patients following surgical intervention.

    Article  CAS  Google Scholar 

  • Edwards BS, Edwards WD, Edwards JE. Ventricular septal rupture complicating acute myocardial infarction: identification of simple and complex types in 53 autopsied hearts. Am J Cardiol. 1984;54:1201–4. Analysis of the morphology of postinfarction ventricular septal rupture.

    Article  PubMed  CAS  Google Scholar 

  • Fananapazir L, Bray CL, Dark JF, Moussalli H, Deiraniya AK, Lawson RA. Right ventricular dysfunction and surgical outcome in postinfarction ventricular septal defect. Eur Heart J. 1983;4:155–67.

    Article  PubMed  CAS  Google Scholar 

  • Heitmiller R, Jacobs ML, Daggett WM. Surgical management of postinfarction ventricular septal rupture. Ann Thorac Surg. 1986;41:683–91.

    Article  PubMed  CAS  Google Scholar 

  • Honey M, Belcher JR, Hasan M, Gibbons JR. Successful early repair of acquired ventricular septal defect after myocardial infarction. Br Heart J. 1967;29:453–6.

    Article  PubMed  CAS  Google Scholar 

  • Komeda M, Fremes SE, David TE. Surgical repair of postinfarction ventricular septal defect. Circulation. 1990;82(suppl IV):243–7. Sets out surgical modifications that aim to reduce ventricular cavity distortion.

    Google Scholar 

  • Konstantinides S, Geibel A, Kasper W, Just H. Noninvasive estimation of right ventricular systolic pressure in postinfarction septal rupture: an assessment of two Doppler echocardiographic methods. Crit Care Med. 1997;25:1167–74.

    Article  PubMed  CAS  Google Scholar 

  • Lee EM, Roberts DH, Walsh KP. Transcatheter closure of a residual postmyocardial infarction ventricular septal defect with the Amplatzer septal occluder. Heart. 1998;80:522–4.

    PubMed  CAS  Google Scholar 

  • Mann JM, Roberts WC. Acquired ventricular septal defect during acute myocardial infarction: analysis of 38 unoperated necropsy patients and comparison with 50 unoperated necropsy patients without rupture. Am J Cardiol. 1988;62:8–19. Analysis of the morphology of postinfarction ventricular septal rupture.

    Article  PubMed  CAS  Google Scholar 

  • Menon V, Webb JG, Hillis LD, Sleeper LA, Abboud R, Dzavik V, et al. Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: a report from the SHOCK Trial Registry. J Am Coll Cardiol. 2000;36:1110–6. Describes the changes in the nature of postinfarction ventricular septal defect in the thrombolysis era.

    Article  PubMed  CAS  Google Scholar 

  • Moore CA, Nygaard TW, Kaiser DL, Cooper AA, Gibson RS. Postinfarction ventricular septal rupture: the importance of location of infarction and right ventricular function in determining survival. Circulation. 1986;74:45–55.

    Article  PubMed  CAS  Google Scholar 

  • Norell MS, Gershlick AH, Pillai R, Walesby R, Magee PG, Wright J, et al. Ventricular septal rupture complicating myocardial infarction: is earlier surgery justified? Eur Heart J. 1987;8:1281–6. Discusses the merits of early intervention versus the earlier philosophy of prolonged support followed by delayed surgery.

    PubMed  CAS  Google Scholar 

  • Parry G, Goudevenos J, Adams PC, Reid DS. Septal rupture after myocardial infarction: is very early surgery really worthwhile? Eur Heart J. 1992;13:373–82.

    Article  PubMed  CAS  Google Scholar 

  • Pretre R, Stalder N, Ye Q, Grunenfelder J, Jenni R, Turina MI. Surgical repair of postinfarction structural failure of the posterobasal part of the heart. Ann Thorac Surg. 1999;68:2152–7.

    Article  PubMed  CAS  Google Scholar 

  • Pretre R, Rickli H, Ye Q, Benedikt P, Turina MI. Frequency of collateral blood flow in the infarct-related coronary artery in rupture of the ventricular septum after acute myocardial infarction. Am J Cardiol. 2000;85:497–9. Analysis of coronary angiographic findings in patients with postinfarction ventricular septal rupture.

    Article  PubMed  CAS  Google Scholar 

  • Rhydwen GR, Charman S, Schofield PM. Influence of thrombolytic therapy on the patterns of ventricular septal rupture after acute myocardial infarction. Postgrad Med J. 2002;78:408–12.

    Article  PubMed  CAS  Google Scholar 

  • Sanders RJ, Kern WH, Blount SG. Perforation of the interventricular septum complicating myocardial infarction. Am Heart J. 1956;51:736–48. Outcome data from the time before surgical intervention was possible.

    Article  PubMed  CAS  Google Scholar 

  • Skehan JD, Carey C, Norrell MS, de Belder M, Balcon R, Mills PG. Patterns of coronary artery disease in post-infarction ventricular septal rupture. Br Heart J. 1989;62:268–72. Analysis of coronary angiographic findings in patients with postinfarction ventricular septal rupture.

    Article  PubMed  CAS  Google Scholar 

  • Szkutnik M, Bialkowski J, Kusa J, Banaszak P, Baranowski J, Gasior M, et al. Postinfarction ventricular septal defect closure with Amplatzer occluders. Eur J Cardiothoracic Surg. 2003;23:323–7.

    Article  CAS  Google Scholar 

  • Takahashi T, Kadoba K, Taniguchi K, Sawa Y, Imagawa H, Masai T, Matsuda H. Repair of postinfarction ventricular septal defect on a beating heart. Ann Thorac Surg. 1996;61:1816–7.

    Article  PubMed  CAS  Google Scholar 

  • The GUSTO Investigators. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med. 1993;329:673–82.

    Article  Google Scholar 

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7.1 Electronic Supplementary material

Below is the link to the electronic supplementary material.

309054_1_En_7_MOESM1_ESM.avi

Apical post-AMI defect from the left perspective (AVI 1020 kb)

309054_1_En_7_MOESM2_ESM.avi

Apical post-AMI defect from the right perspective (AVI 1016 kb)

Large post-AMI VSD at the base of the heart, below mitral valve (AVI 7016 kb)

309054_1_En_7_MOESM4_ESM.avi

View of the interventricular septum with both discs of the device correctly deployed (AVI 1437 kb)

309054_1_En_7_MOESM5_ESM.avi

“En face” perspective visualizing the device from the left perspective (AVI 1442 kb)

309054_1_En_7_MOESM6_ESM.avi

“En face” perspective visualizing the device from the right perspective (AVI 1481 kb)

Video 7.1

Apical post-AMI defect from the left perspective (AVI 1020 kb)

Video 7.2

Apical post-AMI defect from the right perspective (AVI 1016 kb)

Video 7.4

View of the interventricular septum with both discs of the device correctly deployed (AVI 1437 kb)

Video 7.5

“En face” perspective visualizing the device from the left perspective (AVI 1442 kb)

Video 7.6

“En face” perspective visualizing the device from the right perspective (AVI 1481 kb)

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© 2014 Springer-Verlag London

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Faletra, F.F., Perk, G., Pandian, N.G., Nesser, HJ., Kronzon, I. (2014). Closure of Post-AMI Ventricular Septal Defect. In: Real-Time 3D Interventional Echocardiography. Springer, London. https://doi.org/10.1007/978-1-4471-4745-9_7

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  • DOI: https://doi.org/10.1007/978-1-4471-4745-9_7

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4744-2

  • Online ISBN: 978-1-4471-4745-9

  • eBook Packages: MedicineMedicine (R0)

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