• Athina MarkouizouEmail author


Radiotherapy is well known that plays an essential role in the management of gynecological malignancies. It is delivered either for palliation or radical approach and often combined with other forms of treatment, such as surgery or chemotherapy. Though elderly patients tolerate irradiation treatment well, their particular physiological aspects should be always considered for the appropriate therapeutic decision making. The entry of technical advances in conjunction with the variability on treatment schedules makes the elder patients not to decline the irradiation when indicated while providing lower toxicity, rapidity of treatment delivery, and no impairment of therapeutic effectiveness. The encouragement of accrual enrolment of elder patients in prospective studies aiming to identify the best tailored irradiation treatment focusing on toxicity, efficacy, basing on their physiological and psychological aspects is mandatory.


Elderly Radiotherapy Gynecological Malignancies 



External beam radiotherapy


Postoperative radiation therapy for endometrial carcinoma trials


High-intermediate risk


Endometrial cancer


Local recurrence rate


Health-related quality of life


No adjuvant treatment


Postoperative radiation therapy for endometrial carcinoma trials


Vaginal brachytherapy


Gynecologic Oncology Group trials


Disease-free survival


Overall survival


Disease-specific survival


Rate range


Cancer-specific survival




Radiation Therapy Oncology Group


Intensity-modulated radiotherapy


Surveillance Epidemiology and End Results


National Cancer Institute




International Federation of Gynecology and Obstetrics




Low-dose rate


Specific survival rates


High-dose-rate intracavitary brachytherapy


Concurrent chemoradiation therapy


High-dose rate






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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  1. 1.Department of Radiation OncologyMetaxa Cancer HospitalPiraeusGreece

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